511 results
JNJ-2607019 is an investigational drug being developed for gastroesophageal reflux disease (GERD) to reduce the complaints of abdominal pain and heartburn in people with this disease. JNJ-26070109 inhibits the gastrin receptor in the stomach. The…
The objectives for the study are:to investigate the safety and tolerability of JNJ-37822681 following single dose administrations in healthy male subjects.to investigate the plasma pharmacokinetic profile of JNJ-37822681 and metabolites after single…
The objective is that 6 standard ligation of hemorrhoidal arteries is as effective as doppler guided.
What is the resorbability of rigid 30% macroporosity TCP wedges after OWHTO. Is complete resorption possible?
1. To determine the efficacy of web-based CBT for adolescents with CFS;2. To determine which factors contribute to this efficacy;
Aim of the study is to investigate if application of a dermal substitute in combination with topical negative pressure can improve the quality of the scar in burn wounds.
To describe the safety and tolerability of up to 5 years denosumab administration as measured by adverse event monitoring, immunogenicity, and safety laboratory parameters in subjects who previously received denosumab.
To study the impact of treating potentially modifiable vascular risk factors in HIV-1 infected patients by a nurse-led vascular intervention program
Primary• To determine the safety profile of oral topotecan in subjects with cancer andmildly moderately or severely impaired renal function (Groups C, D and E) compared to subjects with cancerwhose renal function is normal and who have received…
Het doel van de studie is het vaststellen van de incidentie van diep veneuze trombose na artroscopie van de schouder bij patiënten die geen trombose profylaxe krijgen, middels een bilaterale uitgebreide compressie echo duplex van de benen en de…
The objective of this study is to assess the efficacy and safety of adalimumab in combination with a topical treatment for the treatment of patients with moderate to severe chronic plaque psoriasis.
To compare postoperative pain after anterior inguinal repair with mesh according to Lichtenstein or open repair with Polysoft® mesh
- research the efficacy of a new group cbt: 'to control thoughts and feelings'- to indicate whether a randomized controlled study is advisable
Objectives1. Reduction of defect size after MMS with a pre-treatment with imiquimod 5% cream2. Reduction of tumour size of large nodular facial BCC, after pre-treatment with imiquimod 5% cream.3. Improvement of cosmetic results.4. Histological…
Objective: The principal objective is to evaluate the safety and efficacy of two doses of BOTOX (200 Units or 300 Units) compared with placebo injected into the bladder wall in patients who have urinary incontinence due to neurogenic detrusor…
To test whether 100 mg doxycycline inhibits aneurysm growth
To provide long-term safety data for the use of AMG 531 in thrombocytopenic subjects with IPSS low or intermediate-1 risk MDS.
primary • To determinne the safety and tolerability of sorafenib when administered in combination with gemcitabine and carboplatin.• To determine the maximal tolerated dose (MTD), dose limiting toxicity (DLT) and optimal treatment schedule of…
-To determine the feasibility and the maximum tolerated radiation dose in HDRBT of the rectum after EBRT in rectal cancer patients who are unfit for surgery or refuse surgery-To determine the incidence and severity of acute and late toxicity of EBRT…
To investigate the association between two polymorphisms of the HTR2C gene (5-HT2c-receptor gene) (3813929 C/T and rs1414334: C>G) and metabolic adverse drug reactions in starters with mirtazapine (5-HT2C-receptor antagonist) versus…