315 results
Page 18 of the protocol (v1.0, 4-Nov-2013):The primary objectives of this study are:- To evaluate the efficacy of ciprofloxacin DPI administered BID intermittently for 28 days on study treatment / 28 days off study treatment or 14 days on study…
The effects of intravenous TRH administration on brown adipose tissue activity in healthy, lean men.
To investigate whether BAT tissue can be activated by intravenous administration of TRH. Secondary objectives are to determine whether intravenous TRH increases the degree of cardiovascular sympathetic stimulation and the response of skin…
To define the amount of dietary protein required to optimally stimulate post-exercise muscle protein synthesis in the older population.To assess whether co-ingesting 1.5 g of free leucine (contained within 15 g dairy protein) along with 15 g protein…
The specific aim of the project is to determine the efficacy of Spherical Nucleic Acids (SNAs) on psoriasis skin biopsy gene expression in vitro.
The FLAVO-II study will be conducted as a three-armed, randomized, cross-over intervention trial aimed at comparing the effects of chocolate and pure epicatechin on vascular function.
We aim to investigate whether reinstatement of cortical representations are necessary for successful memory retrieval.
This study aims to compare the effects of a training in concrete thinking and a training in positive reappraisal with a control conditions (no specific training instructions) on indices of psychological wellbeing in youth aged 15 to 18. Participants…
The goal of the study is whether to establish if application of combined cyrocompression therapy directly postoperative after hip fracture surgery results in a significant reduction in painperception en whether this reduces the morfine consumption.…
Feasibility of knee motion reproduction method for application in a hinged knee distraction device to apply reliable comfortable hinged knee joint distraction to be tested in future clinical studies.
1) To perform gene mutation analysis in family members of patients carrying a proven mutation in the candidate gene.2) To determine the clinical, biochemical and radiological characteristics of carriers of a mutation in the candidate gene.3) To…
We seek to elucidate the perinatal exposures to DEHP and BPA with the intention of providing evidence for policy makers and manufacturers. It is our hope that less toxic products will be used in health care and in the general population in the…
The primary aim of this study is to find the dose of DHA during pregnancy and lactation that leads to a mean breastmilk DHA of at least 0.7g%.
In this study we would like to investigate the effects of denervation on the cortical representation of finger articulations. We will assess the decodability of six different hand gestures from the American Manual Alphabet in people with an…
We aim to measure the vitamin D status (25(OH)D) and prevalence of vitamin D deficiency in Western and non-Western infants and toddlers aged six months to four years in the Netherlands. We will assess the cross sectional association between vitamin…
Determination of volume and surface area of intramuscular oil depots during body clearance using MRI
The aim of this research is to determine the surface area of an oil depot during oil clearance. This is relevant for the release rate and therefore for the absorbed amount of active substance in blood. The volume is important for the interstitial…
The overall objective is to investigate the efficacy of resveratrol in modulating metabolism and CVD risk profile in patients with COPD. The primary objective is to investigate the effect of resveratrol on CRP as clinical marker of low grade…
The AMACING study aims to evaluate the (cost) effectiveness of guideline prescribed intravenous prophylactic hydration in the prevention of: CIN, decrease in renal function, renal damage, 30-day morbidity and 30-day mortality; taking into account…
To examine the effectiveness of an unsupervised e-health supported neuromuscular training program in combination with usual care in general practice compared to usual care alone in patients with acute lateral ankle sprains in general practice.
To assess the effect of vitamin D supplementation on exacerbation rate in patients with COPD and a vitamin D deficiency.
To compare the effect of oxygenated versus non-oxygenated hypothermic machine perfusion of grafts of DCD category III (awaiting circulatory death - controlled), kidneys aged 50 years or older on kidney graft function.