165 results
The primary objective of this study is to establish the relationships between structural and neural adaptation of human skeletal muscle when muscles are exposed to overstretch and overload through exercise.
Assess amyloid beta clearance from CSF to serum in response to HFCWO in healthy volunteers:- Change from baseline in amyloid beta 40 (ng/ml) in CSFAssess endogenous protein biomarker clearance from CSF to serum in response to HFCWO in healthy…
Investigation of the performance of the Virax Immune COVID-19 kit when tested using blood donations from healthy participants.
This study has been transitioned to CTIS with ID 2023-505835-11-00 check the CTIS register for the current data. PrimaryTo demonstrate the superiority of galcanezumab versus placebo in the prevention of migraine in an adolescent population (12 to 17…
Primary Objective: To test the feasibility of online neuropsychological assessments using the Amsterdam Cognition Scan (ACS) compared to classical neuropsychological assessments in patients with cancers with CNS involvement.
In the current study we aim to measure the postprandial amino acid uptake kinetics of barley rice protein, and compare this to pea protein. A benchmark protein (whey) will be included for comparability of amino acid uptake of different protein…
Primary objective 1) To evaluate the usability of the total viQtor solution applied and used 24/7 in clinical practice.This includes the ease of use and/or usability of:the wearable, charger and armband by the primary participants/usersthe *care…
To compare the appearance of dietary protein-derived amino acids in plasma after ingestion of a milk protein powder with different levels of protein glycation in healthy young men.
This study has been transitioned to CTIS with ID 2024-512350-17-01 check the CTIS register for the current data. The aim of this study is to evaluate the feasibility and safety of CYP2C19-genotype-guided p2y12 inhibitor selection in patients who are…
Individualized trajectories of upper arm disease progression in Duchenne muscular dystrophy patients
Main objective1. To assess the longitudinal trajectories of upper arm flexor muscle MRI parameters, muscle force and upper arm function in a cohort of ambulant and non-ambulant DMD patients, to assess the value of this muscle as target for…
To develop an exergame system which helps patients, ICU staff (including physiotherapists), in ameliorating early mobilisation exercises (frequency, intensity and patient and staff experience), finally aiming to accelerated rehabilitation and reduce…
The project*s overarching aim is to diminish respiratory disease burden in moderate-late preterm born infants in their first 18 months of life. We have formulated the following specific objectives: 1. Determine whether the introduction of our follow…
The objective of this study is to assess the prognostic value of early perfusion changes and infarct evolution detected with magnetic resonance imaging (MRI) acquired directly after EVT.
The primary objective of this study is to investigate whether the use of the EOS calculator safely reduces antibiotic exposure in newborns with suspected EOS in the first 24 hours after birth compared to the current Dutch guidelines.Secondary…
The primary objective is to develop a disease model predicting clinical meaningful changes based on a combination of results of tests on clinical function, muscle MRI, echocardiography and circulating biomarkers applicable in various stages of…
Primary Objective: We aim to provide a clear phenotype of the immune system in patients with FOXP1 syndrome. Secondary Objectives:We aim to correlate the immunophenotype of patients with FOXP1 syndrome with frequency and type of infections reported…
The primary objectives of the study are as follow:1) To assess usability and adherence to a T2T strategy implemented through a digital e-health tool website (i.e. do physicians work through all aspects of the website and take part in all the T2T…
Our main objective is to investigate the feasibility and cognitive effects of applying self-regulation strategies learned from large-scale brain network balance neurofeedback training on active memory suppression in a PTSD patient population.
The primary objective of the study is to predict the effect of a given ecological momentary intervention (either ReApp or Imager) based on acquired baseline measures. Further, the use of DBMs to generate an objective stressor reactivity score is…
This study has been transitioned to CTIS with ID 2023-503793-20-00 check the CTIS register for the current data. The main purpose of this study is to learn whether asundexian works better than placebo at reducing ischemic strokes in participants who…