16 results
The primary objective of this study is to assess the comparative safety and efficacy ofAztreonam Lysine for Inhalation (AZLI) and Tobramycin Nebuliser Solution (TNS) in adultand pediatric cystic fibrosis (CF) patients aged 6 years or older with…
To conduct a randomised trial to test the hypothesis that the experimental condition, i.e. the intervention*Gezin aan bod*, is superior to 'care-as-usual' in exerting a positive effect on a number of the risk factorsfor problematic…
To assess in a cohort of patients with established FAP:1 The efficacy of MPA in terms of reduction of number of colonic polyps, by means of Endoscopic Appearance of Polyposis (EAP) index.2 The effect on histological parameters and biological…
Determining the prevalence of testicular microlithiasis in Down syndrome.
Primary: Dose finding for a twice daily regimen for PSZ as prophylactic treatment in children with CGD, based on the exposure to PSZ measured by PSZ trough levels.Secondary:To determine the tolerability of PSZ as prophylactic treatment in children…
The objective of this research is to develop a method which can identify among all consanguineous couples the ones which are at high risk.
This project aims at evaluating the reliability, validity, and the practical relevance of the SDQ Self Report compared to KIVPA (a Dutch questionnaire to detect psychosocial problems in adolescents). The study findings may support the Dutch policy…
1. To detrrmine the applicability of standard energy expenditure prediction equations for accelerometry in measuring physical activity in children with musculoskeletal and other chronic diseases (see below).2. To develop disease specific prediction…
The prime objective of this research project is to assess the feasibility of a low-threshold, accessible, preventive cognitive-behavioural therapeutic intervention with parental support for grieving children and their parents, and to get a first…
Developing an evidence-based guideline for the diagnosis and surgical treatment of children with severe gastro-esophageal reflux disease.
The objective of this project is examining whether the empowerment program POWER reduces the risk on marginalization of youngsters from immigrant families (with an elevated risk).In this project the following research questions will be answered.(1)…
Hypothesis: the Internet guided self-help intervention is effective in reducing depressive and anxiety symptoms in adolescents compared to a waiting-list control group.
To improve physical activity levels and physical activity patterns in children with JIA by means of cognitive behavioural training based on the social cognitive theory and the health promotion model, delivered by internet and supported by group…
The objectives are to:A. Identify subjects with VWD who may benefit from prophylaxis by determining patterns of bleeding prior to evaluation for enrollmentB. Study the effect of prophylaxis on bleeding frequencyC. Establish optimal treatment…
Analyze the protective effect of levocetirizine (LEV), through the direct antagonism of airway H1 receptors and the inhibition of the release or production of other inflammatory mediators, against exercise induced airway obstruction.
1) To examine the effect of a 12-week multidisciplinary treatment on endothelial function, intima-media thickness and blood cholesterol in obese children (8-17 years).2) Investigate the changes in vascular function in obese children (8-17 years).