125 results
The objective of this study is to statistically identify the optimal level of contact-pressure for DBT. *Optimal* is defined as a weighed sum of three clinical interests: as high as possible lesion conspicuity, as low as possible absorbed glandular…
To study the potential of alkaline phosphatase to protect against ischemia-reperfusion injury in living donor kidney transplantation.
Primary objectives:1. To quantify physical activity, sports participation and exposure according to age, haemophilia severity and joint status;2. To assess the incidence of sports-related injuries in those who participate in sports at least once…
Prospectively investigate whether ciprofloxacin, administered as antibiotic prophylaxis in patients treated for haematological malignancies (with or without gastro-intestinal mucositis), in the currently recommended dosing regimen (500 mg orally or…
The aim of this study is to improve our understanding of the development of late effects after cancer treatment and reveal potential targets for intervention/prevention. Therefore we will investigate mechanisms behind the early ageing phenotype…
This study has been transitioned to CTIS with ID 2024-517236-22-00 check the CTIS register for the current data. The main purpose of this study is to assess the hypothesis that a strategy with ASA 100mg/day and intensive blood pressure treatment (…
The VAT study aims to investigate which factors influence and predict the different areas of recovery. VAT also examines how the content of voices that patients hear should be mapped and registered. We examine whether these factors can predict…
The objective is to evaluate if topical benzoyl peroxide reduces the presence of C. acnes on the skin of the shoulder compared to a topical placebo?
The primary objective is to identify joint trajectories of mobility and perceived fatigue from hospital admission to 6 months post-discharge in acutely admitted hospitalized older patients. Secondary objectives are:(1) to explore associations of…
The aim of this Eat well, Move well intervention is to study the effect (in addition to DOW) on physical performance, nutritional status, delaying or preventing institutionalization, number of falls, and quality of life of frail older adults with…
The main objective of this study is to investigate whether music as an intervention is effective in reducing the occurrence of postoperative delirium. Secondary objectives are the effects of perioperative music on pain, anxiety, medication use,…
To investigate whether prophylactic clipping (PC) after endoscopic mucosal resection (EMR) of a flat polyp in the colon prevents delayed bleeding (DB) and is cost-effective.
Primary Objective:The primary aim of this study is data collection of continuous noninvasive arterial pressure waveform signals with the ClearSight (CS) finger cuff, continuous invasive arterial pressure waveform signals when an arterial cannula is…
The objective of this open-label extension (OLE) study is to assess the effect of long-term safety and treatment effect of Voxelotor in participants who have completed treatment in Study GBT440-031, using the following parameters:- Safety based upon…
Aims of the study:1. To evaluate the effect of a guided self-help resilience training for pregnant women with depressive symptomatology on:a) primary outcomes: maternal depressive symptoms and resilience; andb) secondary outcomes including maternal…
Objective: We propose the Amsterdam Infant Microbiome Study (AIMS). The general objective of AIMS is to establish a research infrastructure that allows for explorative research on the development of the microbiome in relation to healthy growth and…
The current project aims to address the three barriers that obstruct children from profiting optimally from CBT. For this purpose, an easy accessible, online, CBT-based training for anxious children (aged 8-13 years) will be developed and assessed…
To compare the effect of umbilical cord clamping after cardiopulmonary stabilisation (Physiological Based Cord Clamping; PBCC) to standard care (Time Based Cord Clamping; TBCC) on intact survival and health care costs in preterm infants.
To investigate of the accelerated aging process in morbid obese individuals can be stopped or reversed by bariatric surgery. We also want to investigate whether the aging process in muscle tissue, liver tissue and fat tissue is comparable to the…