135 results
To assess the prevalence of LDL-C >1.8 mMol/L in a subgroup of very high risk patients with ASCVD, who remain at a very high-residual risk for ACS, despite treatment with high-intensity statins in combination with ezetimibe. This subgroup of…
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
The objectives are firstly that Love is... promotes the healthy sexual development by increasing knowledge and positive attitudes towards sexuality. Secondly, characteristics of adolescents who do not improve from the general prevention program are…
In this study we want to investigate how a perturbation-based treadmill training with cognitive dual-task improves daily life gait stability in older adults compared to conventional treadmill training with cognitive dual-task.The results of this…
The aim of this study is to investigate the amount of clinically relevant SRML (defined in this study as *5% muscle loss within one week measured by the cross sectional area (CSA) of the different muscles) in patients after major abdominal surgery…
One of the primary goals is to establish whether students in the first grade of secondary vocational education receiving the multimodal school-based stepped approach towards preventing suicidal behaviours and depression show a clinically significant…
To determine if SSA are effective in decreasing transfusion requirements and improving quality of life while being cost-effective.
The objective of this study is to assess the feasibility and initial safety and performance of the TRVD* System when used for renal venous decongestions in patients with acute decompensated heart failure.
The primary objective of the study is to investigate the effectiveness of the adapted eHeadspace Generation Next (GN) website in the Netherlands. Secondary objectives are to investigate the utility of a smartwatch for prognosis and the development…
Whooping cough is very contagious. Earlier research shows that family members of a child with whooping cough are often also infected with the pertussis bacterium. However, not everyone who is infected with the bacterium develops symptoms. In this…
Primary objective:To investigate Pertussis Toxin (PT) specific antibody responses 1 month following the second aP vaccine given at 5 months of age to infants whose mothers have (Arm 1) or have not (Arm 2) received a pertussis booster vaccine during…
Objective: To obtain data to be used for designing a larger scale study on the incidence of 25OHD levels below the recommended level of 50 nmol/l in children in Murmansk, Russia and Groningen, the Netherlands.
Primary objective: To determine if beam walking performance vis-à-vis the traditionally used balance outcomes predicts more accurately fall risks and falls.Secondary objectives: To determine: 1. Reliability and 2. Lifespan and patient reference…
To assess how measures of microvascular function on 7T MRI in individuals from the Rotterdam Study without a history of clinical stroke or dementia relate to:- Exposure to vascular risk factors - Severity of presymptomatic SVD lesions- Cognitive…
To evaluate the effect of Avelle negative pressure wound therapy in reducing postoperative wound complications after mastectomy with flap fixation and closed suction drainage.
This preliminary quasi experimental study aims to explore the experiences of patients using a newly developed VR application as an adjuvant in the treatment of AUD after clinical detoxification in DSM-5 diagnosed AUD patients. This study aims to…
The primary aim of the current research is to gain insight into the background, and the precipitating factors of the suicides among adolescents aged, 10 to 20 years old, in 2017 in the Netherlands, by focusing on five domains and the last period…
To study the effect of sweetener oral rinses on the oral microbiome composition.
Primary objectiveTo determine whether aprotinin can reverse the increased postoperative blood loss, induced by dual anti-platelet therapy in elective non-complex cardiac surgery.Secondary objectiveTo determine whether aprotinin reduces transfusion…
To investigate in our defined HF patient population if monitoring in combination with motivation on physical activity leads to an increase in enrollment rate for cardiac rehabilitation and sustained physical activity after cardiac rehabilitation as…