273 results
The main objective is to study pregnancy rates after using metabolomic profiling added to the selection of viable embryos by morphology, compared to using only morphology.
the objective of the current study is to evaluate the safety and efficacy of enzyme therapy in the Dutch population of patients with MPS I, II and VI; to compare this to the natural course of these diseases; to make an inventory of the direct and…
Primary aim: To investigate whether PET-CT (using [18F]FDG, [18F]Fluoride and [11C]PK11195 as tracers) visualizes inflamed tissues of AS patients, with clinical scores as reference Secondary aim: To investigate whether reduction of inflammation by…
Primary objectives:1) Describe the PD effects on plasma ACTH and serum cortisol upon 100 µg hCRH injection with or without a preceding injection of 10 µg dDAVP 2 hours earlier and study the PK-PD relationship (*Block B*). In particular, the outcome…
The aims of this study are: 1) to evaluate the neoplasia miss-rate of AFI in patients with longstanding UC during colonoscopic surveillance; 2) to evaluate the feasibility of miniprobe-based confocal endomicroscopy in these patients; 3) to compare…
A pilot-study to the feasibility of a simple self-patchtest with a PPD containing hair-dye solution. The aim is to investigate whether a 30-minutes application of a patch-test gives a positive reaction in individuals who have a proven contact…
To explore the prevalence of testosterone insufficiency in HIV-infected women and the associated sexual problems, fatigue , depression and quality of life.
Assessing hereditary and aquired determinants of ETP. Evaluating the use of ETP as predictive stand alone test for recurrent DVT and bleeding complications due to anticoagulation therapy in comparisson with the current prediction methods.
The main objectives of this study are to describe behavioural problems in children aged 0 to 4 years and posttraumatic stress symptoms in children aged 8 to 17 years and to study the course and determinants of these problems. Further, this study…
The primary aim of this MAPCAT-study is to investigate whether pharmacokinetics of clopidogrel differ significantly betwen different clinical scenarios. A second aim is to study specifically whether genetic polymorfisms influence these…
1-objective: to get insight in objective (urodynamic) and subjective (questionnaire) changes of the lower urinary tract after laparoscopic robot assisted radical prostatectomy, Intensity modulated radiotherapy, I-125 brachytherapy.2-To create…
The development of a valid and reliable test intended to measure functional motor activities in daily life of children with DCD.
The aim of this study is assessment of right ventricular function: a comparison between MRI and real-time 3-D echocardiography (RT 3-D echo). We have the following research questions: 1) Is assessment of right ventricular (RV) function with RT 3-D…
To determine the diagnostic accuracy of FDG-PET-CT (pre-treatment and in the early phase of treatment) in the prediction of local control after primary radiotherapy with or without chemotherapy for functionally inoperable HNSCC.
To evaluate whether the 3M BacLlte system has a comparable sensitivity and specificity with the hitherto used conventional culture protocols
Primary objective is to investigate the feasibility of Hexvix® blue light URS. Secondary objectives are to determine the diagnostic value of Hexvix® blue light URS as compared to digital and fiberoptic white light URS, and to assess safety and…
The aim is to study if Neurofeedback can be an applicable intervention.for survivors of childhood brain tumours. The QEEG wil be investigated whether under or overactive brainareas exist which can be trained. This study will also investigate whether…
The aim of the present study is to evaluate whether there is an association between biomarkers (hs-CRP and BNP)
The goal of this research is to determine whether multi-unit microneurography can be a practically useful technique for recording human muscle-afferent signals, and to determine which fiber types are present in the recorded signal to and from the…