32 results
The main objective is to improve treatment with clotting factor concentrate of patients affected by RBDs by collecting and analysing data on the patients genotype, laboratory phenotype and clinical severity.Secondary objectives are to gain…
Primary objective of this study is to assess the reliability and validity of the neuromuscular parameters of ankle joint impedance estimated by nonlinear SIPE technology in children with CP compared to current clinical manual tests and gait analysis…
The overall objectives of this proposal are to develop two indices capable of measuring intestinal damage, and, separately, inflammatory disease activity in Pediatric Crohn's disease by means of Magnetic Resonance Imaging with Enterography…
To investigate whether children with a history of Kawasaki disease have an increased IMT and arterial stifness compared to their healthy siblings.
To find out if the mean thyroid volumes of healthy 10-12 and 17-18 years old Dutch children and adolescents are the same or larger than in the late nineteen nineties, and if the dietary iodine intake of these children and adolescents has decreased…
The prime objective of the IMPROvED project is to develop a clinically robust predictive blood test for pre-eclampsia, using innovative technologies and utilising novel metabolite and protein biomarkers. This blood test is targeted to all first time…
Primary objective:To determine sAF levels in children and young adults with T1DM and in children with obesity with or without T2DM and determine the correlation between sAF levels and HbA1c in children and young adults with T1DM and in children with…
Primary objective is to assess the reliability and assess the reliability and construct validity of the Repetitive Movement Test (RMT) as a measure of spasticity in children with CP scheduled for ITB treatment, between 6-18 year.
To develop and examine the test-retest reliability of a wheelchair skills test for children
To study the validity and usefulness of three immunological assays to improve knowledge on the course and diagnosis of sesame seed allergy in sesame seed allergic patients with proven anaphylaxis. In the first place, the CAP inhibition assay is used…
Aim: To investigate the performance of the new ESPGHAN diagnostic criteria for celiac disease in practice in different European countries.Primary aim: To evaluate whether the omission of biopsies in selected pediatric cases does result in certain…
To test the reliability and validity of the IPMDS in children with mitochondrial disorders.
1. To determine if auto-antibodies against the re-expressed protein exist in the peripheral circulation in patients with EB and revertant mosaicism and compare this incidence to the group of patients with EB and without revertant mosaicism. 2. To…
The objective of this study is to assess the diagmostic accuracy of microMRI to detect ROD in children with ESRD and metabolic bone disease by oxalosis in patients suffering from oxalosis.
To obtain normal values of biventricular volumes, ejection fraction and wall mass using MRI SSFP sequences at 3Tesla.
The objective is to examine the physical fitness of children with moderate to severe intellectual disability.
The overall aim of this study is to find objective and sensitive markers to predict short term and long term food challenge outcome. Primary Objectives: - Can we predict (severity of) short- and long-term food challenge outcome with clinical and…
Aim is to determine the usefulness of the Autism Quotient as a screener for autism spectrum disorders in 15-18 years old boys. Possibly comorbidity like conductdisorders lessen the usefulness of the autism qotient as a screener because some boys…
The main goal of the study is to characterize the perception of reflexives and pronouns in normally developing normal-hearing, hearing-impaired and cochlear implanted children. The proposed project consists of a longitudinal study spreading over 5…
The objective of this research is to see if this way of treating a patient ensures a quicker diagnosis, which results in lessabdominal pain for the patient.