1020 results
To get insight into the prevalence of a whole range of psychiatric symptoms of parents of children who have been admitted to an outpatient clinic for child and adolescent psychiatry for various psychiatric symptoms and the parent-offspring…
1. To determine demographic, clinical, and brain morphological and functional predictors for IST, and; 2. To examine their associations with the level of increase of seizure threshold (*ST) during the ECT course, as measured at every sixth ECT-…
Primary objective1.To determine the characteristics, frequency and severity of vascular, metabolic and hormonal side effects of angiogenesis inhibitors and EGFR inhibitors.Secondary objectives1.To investigate if steroid profile, indol profile,…
Primary: To find out which areas in the brain play a part in the maintenance of tinnitus, and what the roles of those areas are. This will be done using BOLD response fMRI imaging.Secondary: 1. To find out which areas in the brain play a part in the…
Primary objectives:1. To analyze the exact pathogenic mutations in the TCOF1 gene in TCS 2. To determine the severity, prevalence, natural course within the cohort TCS patients and potential metabolic and physical effects of OSAS in TCSSecondary…
To investigate the relation between a known genetic variation in a set of selected genes involved in the recognition of microorganisms and inflammation and the frequency of respiratory tract infections in a group of children with DS.
We aim to investigate which part of the pulmonary vasculature, the obstructed or non-obstructed, is responsible for the pulmonary vasodilator response.
The relationship between sleep disorders and (reactive) aggression in forensic psychiatric patients.
The primary objective of this study is to examine the relationship between sleep disorders and (reactive) aggression in forensic psychiatric patients in the Forensic Psychiatric Center Dr. S. van Mesdag in Groningen. In addition to this,…
The main objective is to study precision control of trunk posture and associated muscle recruitment in LBP patients and healthy controls during trunk positioning tasks in which postural control is challenged, by increased dead space breathing, by…
To evaluate the blood pressure within the first year of life we will perform a prospective longitudinal study in all newborn patients with the classical form of CAH. To analyze the urinary steroid profile in CAH patients and healthy controls during…
The aim of the present study is to establish intero-interoceptive fear conditioning in healthy participants in a differential conditioning paradigm. We want to make use of *real* interoceptive conditioned stimuli: a low respiratory load and small…
The primary objective of the study is to explore the efficacy of intensive bicycle exercise test to induce cardiac micro-injuries by measurement of serum concentrations of hs-troponin I in healthy volunteers. The secondary objectives of this study…
The aim of the present research proposal is:- to investigate the effect of a dysbalance in lipase expression, induced by selective knockdown, on lipase activity, the accumulation of lipid metabolites and insulin signaling in differentiated…
Primary Objective: characterization of GPBP expression on different subsets of human leukocytesSecondary Objective: functional characterization of GPBP on these cells
The primary objective of this clinical controlled trial is to define the overall effect of adenocorticotropic hormone on coagulation parameters in patients with primary adrenal insufficiency (as diagnosed by their physician by previous short ACTH…
1. To investigate the associations between DSM-IV personality disorder and attachment style. 2. To investigate whether attachment related anxiety and avoidance, as more fundamental personality features than the DSM-IV personality classification,…
There is at present a major focus on the role of the cerebellum in the pathophysiology of dystonia. It is speculated that the cerebellum is an hitherto overlooked yet fundamental part of the abnormal sensorimotor network that drives dystonia. This…
To observe the possible relationship between central, conventional hemodynamic parameters with relatively new peripheral, regional perfusion parameters in two versions of a model with controlled vasocontriction (cooling) - vasodilation (heating)
This study aims to identify the specific environmental influences that cause discordance in neuroticism scores in MZ twin pairs. We hypothesize that the development of high neuroticism is due to having experienced more severe and longer lasting…
To find out the fate of aneuploid blastomeres