6380 results
Primary objective:- To study the impact of community acquired pneumonia in children on persistent symptoms and quality of life, from admission in hospital until one year after discharge.Secondary objectives:To investigate/assess:- The association…
The aim of the current study is to determine the transport functionality, integrity, and viability in intestinal tissue obtained from patients who are expected to have a disturbed intestianl functionality due to severe obesity.
Investigating the function of monocytes and their precursor cells originating from circulation, bone marrow, and spleen in the context of ovarian cancer.
The aim of this study is to assess the position and alignment of the Atlas, as measured by the angles between the atlas and the surrounding vertebrae in healthy participants, patients with tension headache, and patients with chronic whiplash-…
The primary objective of this study is to investigate the effect of 26 weeks of supplementation with three different dietary fibres (chicory inulin, resistant dextrin, and seaweed polysaccharide) compared to a placebo (maltodextrin) on microbiota…
Primary objectives: 1.1) To investigate to what extent the different functions of the cerebral microvasculature are impaired in type 1 diabetes; and 1.2) To investigate to what extent the different functions of the cerebral microvasculature are…
The overall aim of this project is to unravel the role of IFN-I in ILD in the known/classified SADs and in ILD with autoimmune features but without a specific SAD diagnosis (IPAF), with as ultimate goal better treatment. Since 13-40% of ILD patients…
We aim to characterize innate anti-viral defence responses in the upper airways of COPD patients.
To examine the effect of adrenergic inhibition on the hypoglycaemia induced inflammatory response (e.g. leukocyte phenotype, cytokines, inflammatory proteins) by performing a hyperinsulinaemic hypoglycaemic glucose clamp alongside infusion of α-ARA…
Primary objective:i. Investigate cerebrospinal fluid (CSF) polyol concentrations in patients following traumatic brain injurySecondary objectives:i. Investigate the association between plasma glucose, CSF glucose and CSF polyols following traumatic…
Identifying the (immune) cell composition, co-localization, functions, and alterations as well as blood and lymph vessels reorganisation in the human*s dura, arachnoid and pia mater, and skull bone marrow in high-grade glioma patients as compared to…
The aim of the present study is to investigate the effect of a microalgae (Hematoccocus pluvialis) on the stress response and mental wellbeing in jong adults.
Research objective: Transcriptome data from main immune cell types (monocytes, CD4+ and CD8+ T cells, B-cells, NK cells) of post-COVID patients are analyzed using STP technology. STP-activity results are interpreted in combination with clinical…
This study aims to answer the following questions: 1. Is there a difference in the time to onset of the first symptom between HH and NH?2. Is there a difference in the severity of symptoms between HH and NH?3. Is there a difference in the time to…
In adults patients with ischemic stroke and transient ischemic attack, how often does (subclinical) AF occur?
To determine whether the ClinRO and PRO are valid and reliable measures for use in intervention trials, specifically:1. Evaluate the reliability and validity of the proposed ClinRO protocol to assess freezing of gait in individuals living with…
By using advanced respiratory monitoring, we will aim to gain more understanding about the physiological effects and potential benefits of FCV in comparison to VCV in patients with an exacerbation of their asthma or COPD. We hypothesize that FCV in…
Primary 1) Establish whether HTx induces a trained immunity phenotype of circulating mono-cytes in pediatric and adult HTx patients, and compared to healthy controls.2) Investigate whether trained immunity phenotypes in pediatric and adult HTx…
The primary objective of this study is to compare lifestyle factors, dietary behaviours, environmental factors and pre-obesity risk markers between shift workers and non-shift workers from the industrial sector and the health care sector.
With this study we want to test the user experience of the prototype app and to develop a method to identify subtypes of post-covid patients and link this to demografic, medical and sociopychological characteristics as predictors.