128 results
To determine: 1) How neuropsychiatrich problems change over time during the first year after stroke; 2) Which determinants are related to the course of neuropsychiatric problems over time during the first year after stroke; 3) What are the…
Mainstreaming of germline genetic tests in regular healthcare is feasible for healthcare professionals and acceptable for both patients and healthcare professionals
"The main objective of this trial is to assess long-term performance and obtain real-world experience with the bi-hormonal fully closed loop system (Inreda AP®)"
The test product supports normal physical growth in healthy term infants
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
Objective The objective of this study is to assess which risk scoring model is most cost-effective for the discrimination between benign and malignant ovarian tumors that guides referral decisions for women with ovarian tumors in the Netherlands…
The main aim of the proposed study is to 1) assess the habitual consumption of raw cow*s milk among a large population of adult dairy farmers; 2) assess the association between raw cow*s milk consumption and inflammation-related, auto-immune and…
The primary objectives of this study are 1) to assess the factors and considerations that play a role in the decision-making process of either multifetal pregnancy reduction or maintaining a multifetal pregnancy, and 2) to assess the emotional…
Primary Aim: We aim to determine markers for NOX2-mediated insulin-independent glucose uptake signalling pathways, mitochondrial function, myokine secretion both at rest and after a bout of acute exercise in individuals with T1DM and healthy…
Primary Objectives* To investigate the intra-variability (day-to-day) of glucocerebrosidase pathway biomarkers in HV, PD-GBA+ and PD-GBA-Secondary Objectives* To investigate the intra-variability (within-day) of glucocerebrosidase pathway biomarkers…
The objective of this exploratory trial is to explore the acute and chronic effects of daily olive leaf extract supplementation on muscle energy and fatigue in healthy male adults
To assess the spatial topographical representation of anger and behavioural inhibition in the cerebellum.
* Characterize the plasma and Cerebrospinal Fluid (CSF) time concentration profile of 2-AG, 1-arachidonoylglycero (1-AG) over 24h and 16h period, respectively.* Determine the optimal sampling frequency of 2-AG, 1-AG for future studies. * Establish…
Replication study to assess dietary protein requirements in young, healthy men.
The primary objective of this study is to examine whether the in vitro cellular transfection efficiency of PF14-mRNA nanoparticles is higher in medium supplemented with plasma or serum.
To explore, whether markers of mitochondrial dysfunction measured in isolated PBMCs or immune cell subpopulations differ between subjects with mitochondrial disorders and cardiomyopathy and healthy volunteers.
Phase 1: Assess reliability of advanced respiratory muscle ultrasound imaging in healthy subjects and congenital myopathies/muscular dystrophies. Phase 2: assess two year follow-up of respiratory function using advanced respiratory muscle ultrasound…
Primary Objective: Does DBS result in cognitive changes in patients with OCD on the long term? Secondary Objective(s): Does DBS result in personality changes in patients with OCD on the long term?Are certain cognitive profiles associated with…
To investigate the effect of whey and casein ratio of IFT on intragastric behavior, gastric emptying and postprandial plasma metabolome
To assess whether co-ingesting keto-analogues of branched-chain AAs along with protein during HD can attenuate HD-initiated muscle catabolism.