248 results
Our experiment will assess the respective role of the mirror neuron system (MNS) and theory of mind areas for understanding someone else*s immediate intentions and state of mind (prior intention). We want to test the hypothesis that making…
The assessment of the duration of the cellular immunity to Bordetella pertussis after an extra ACV booster and the relationship between the memory B- cells and antibody responses. The methods used in the study are:B- and T- cell memory responses and…
Primary: To provide insight in the prevalence of diagnosed cases of IgG-subclass and/or antipolysaccharide antibodydeficiency in Dutch children. Secondary: To provide insight in the diagnostic process, the clinical presentation, the therapies used…
Primary1. To examine whether psychological factors moderate the effect of the objectively assessed clinical CRT-D response on quality of life in patients with CHF.Secondary2. To examine whether psychological factors moderate the effect of the…
We will evaluate the acute effects of GH on, and its relation with, cognition in healthy subjects. The present proposal focuses on the following questions:1. Does an acute rise of plasma GH levels have a (beneficial) effect on cognitive performance…
Investigating the influence of Transcranial Magnetic Stimulation (TMS)-disruptions on the neural processes in the areas involved in the adaptation abilities of the human oculomotor system.
Identifying subsets of Crohn's disease (CD) at risk for poor outcomes is a priority in pediatric CD research. Having the ability to predict patients more likely to relapse, to be refractory to therapy or to develop complications may enable…
Examining the neural basis of perceiving self-conscious emotions; in order to obtain more knowledge about the function of these emotions.
In this study, we will systematically investigate the influence of distractors on target processing in patients with lesions to the frontal, parietal and occipital system. This will be measured by eye movements. Furthermore, prism adaptation will be…
To define indications for recently developed, but more expensive, self-expanding metal stents (SEMS) versus cheaper plastic stents in patients with primary or recurrent inoperable malignant extrahepatic common bile duct (CBD) obstruction, based on…
Primary research question:To evaluate the impact of open versus endovascular invasive treatment in different types of surgery (AAA, CEA, LLR) on health status. Secondary research questions:To examine the prognostic impact of quality of life in PAD…
The aim of this study is to determine whether subcutaneous administration of insulin detemir, as compared to NPH insulin, leads to a more pronounced effect on brain glucose metabolism and blood flow in brain regions associated with appetite…
1) To determine the prevalence and the sensitivity for various antibiotics of Staphylococcus aureus in the nose (carrier) of patients visiting the outpatient department of Dermatology.2) To determine the prevalence and the sensitivity for various…
Heart rate variability in obese adolescents in relation to insulin levels during OGTT.
A pilot study
The aim of the project is to study the relation between hyperinsulinemia and changes in autonomic tone in adolescents with obesity. We have chosen to perform a pilot study, because of lack of comparable studies in the literature.
In the proposed experiments we intend to investigate both central and peripheral aspects of fatigue in MS patients using a combination of simultaneously applied techniques; twitch-superimposition, electromyographic (EMG) and force recordings and…
The aim of the current study is to investigate which gene-abnormalities can be related to brain deficits and symptoms associated with schizophrenia.
The core approach of our proposed project is to investigate three aspects of emotional recognition in the Möbius and congenital bilateral facial paralysis populations through observed facial expressions, and the possible link between them, as…
The objective of the study is to determine if a 3D motion platform (to measure vestibular function) and accelerometry and a insole pressure system (to measure balance) can be used in future research on patients with vestibular lesions. For this, we…
The levels of performance decrement for the three blood alcohol concentrations will serve as a historical control for comparing the effects that will be observed with psychoactive drugs in future trials. This will make the results of these future…
Cytotoxic treatment may lead to long-lasting brain damage that can result in persistent cognitive changes and accelerated cognitive decline at an older age. The proposed study will investigate whether chemotherapy causes brain changes different from…