184 results
To determine whether micellar curcumin is able to restore functional lymphocytes in pancreatic cancer patients with stable disease after standard of care treatment.
The purpose of this study is to investigate how well a new dosage form of tildrakizumab is tolerated when it is administered to healthy volunteers. Tildrakizumab (also known as Ilumetri) is no new compound; it is already available on the market as a…
The current study aims to assess the impact of self-quarantine on glycemic control. In addition, this study describes diabetes self-management, well-being and distress in Dutch patients with type 1 and type 2 diabetes, during a nationwide period of…
The primary goal of this research project is to study physiological responses of typically developing (TD) children and children with CP (only if the results of TD children are promising) to discomfort induced by the use of technological devices…
Primary Objective: This study aims to analyze cycling gross efficiency, pedalling power symmetry, and hip, knee, ankle kinematics in adults with a transtibial amputation in different foot positions and seat heightsSecondary Objective(s): The second…
The current study investigates which brain areas are related to habituation of pain (using fMRI) and enables a direct coupling with concurrent EEG. We will test the hypothesis that activation of areas in the brain show changes over time as correlate…
Assess amyloid beta clearance from CSF to serum in response to HFCWO in healthy volunteers:- Change from baseline in amyloid beta 40 (ng/ml) in CSFAssess endogenous protein biomarker clearance from CSF to serum in response to HFCWO in healthy…
Investigation of the performance of the Virax Immune COVID-19 kit when tested using blood donations from healthy participants.
Primary Objective: To test the feasibility of online neuropsychological assessments using the Amsterdam Cognition Scan (ACS) compared to classical neuropsychological assessments in patients with cancers with CNS involvement.
In the current study we aim to measure the postprandial amino acid uptake kinetics of barley rice protein, and compare this to pea protein. A benchmark protein (whey) will be included for comparability of amino acid uptake of different protein…
Primary objective 1) To evaluate the usability of the total viQtor solution applied and used 24/7 in clinical practice.This includes the ease of use and/or usability of:the wearable, charger and armband by the primary participants/usersthe *care…
The primary objective of this study is to confirm that the dissolution profiles of a sugar-free and sugared lozenge containing CPC/benzocaine (1.4mg/10 mg) are comparable following a single dose in healthy adult subjects.The secondary objectives of…
Understanding the specific vs. generalized role of the prefrontal cortex for prosocial decision-making. In particular, we want to investigate whether the prefrontal cortex is recruited during the evaluation of the abstract cost-benefit ratio of one*…
The primary objective is to investigate the current prevalence of IAH and severe hypoglycaemia (SH) in individuals with diabetes type 1.The secondary objectives are:- Study the change of IAH over time in individuals with diabetes type 1.- Study risk…
Our main objective is to probe for the functional time-windows of the mid-portion of the left middle temporal gyrus (mMTG) during word comprehension and word production to determine whether the left mMTG is common to both language comprehension and…
Primary Objective:The primary objective of this study is to establish the occurrence of neutralizing antibodies to SPK-GAA capsid in participants with LOPD on an enzyme replacement regimen. Secondary Objective:The secondary objectives of this study…
The overall goal of this study is to assess the detection and discrimination of individual silently or attempted spoken words from the brain area that represents articulation of speech.To address this goal, we defined three primary objectives:1) To…
We aim to provide a neurocognitive account of communicative disabilities in patients with autism spectrum disorder (ASD), focussing on shared representations of a communicative context. We expect that ASD patients show impaired shared…
To investigate the effect of oral curcumin supplementation on different clinical parameters and the gut microbiota composition in patients with diabetes type II, inflammatory bowel disorders (both ulcerative colitis and Crohn*s disease in remission…
To quantify and assess intra- and inter-subject variability in mast cell density among healthy male and female volunteers. Serum tryptase values will also be quantified.