142 results
- The main objective of the laboratory assessment is to get a detailed assessment of children's ability to inhibit behavior. This will be used to test for interplay between personal endownments and social influences in predicting delinquency.…
To investigate which genes are involved in the pathogenesis of obsessive compulsive disorders and associated disorders.
The general objective of this study is to contribute to the knowledge on the approach of the Dutch CPA*s. More specific objectives of this research are: 1. To determine the course of the mental health and quality of life of abused children from 5 to…
To study the effect of ethanol lock therapy on the cure rate of catheter-related infections (CRIs) and on the incidence of (CRI related) venous thrombosis in total parenteral nutrition (TPN) patients with tunneled central venous catheters older than…
Effects will be evaluated in a randomized controlled design. First, the effects of OpKoers on social-emotional outcomes will be compared with a control group. Secondly, the additionalvalue of Samen Sterk will be investigated in relation to both…
To support future scientific research into late effects of treatment for childhood cancer
To determine the value of MRI in a consecutive series of pediatric patients suspected for acute appendicitis
To study the effect of ethanol lock therapy on the cure rate of catheter-related infections (CRIs) and on the incidence of (CRI related) venous thrombosis in pediatric total parenteral nutrition (TPN) patients with tunneled central venous catheters…
The purpose of this study is to compare two different braces in idiopatic scoliosis, by means of body brace interface pressure measurements and conventional spinal x-rays (anterior-posterior).
1) To assess insulin sensitivity and response in critically ill septic neonates and children. 2) To determine protein balance in septic, critically ill children at baseline and during a Hyperinsulinemic Euglycemic Clamp, while receiving standard or…
To identify the abnormalities in the coagulation system leading to VTE and other thrombotic complications and to determine the prevalence of subclinical and clinically manifest thrombophlebitis and/or DVT in a well-defined Dutch VM population.
1. Primary Objective(s) The primary objective(s) of this study are to:* Evaluate the course of disease progression in patients with MPS IIIA who are untreated with any investigational products to inform possible future treatment studies * Determine…
We want to answer following research questions: 1. Is there a difference in physical fitness in children with DCD (age 7-12 years) compared to healthy peers? 2. Is there a relationship between physical fitness and activity/participation and is this…
Inventarisation of the different physical characteristics of SRS at different ages. In this way, differences in phenotype between the 2 diferent causes of SRS will become apparent. Also, with this knowledge, more rpecise and elaborate information…
In this study we aim to elucidate which areas of speech are specifically affected in children and adolescents with classic galactosemia and to sketch a profile of the galactosemic patients* general cognitive functions.
The purpose of this study is to examine the efficacy and safety of 26 weeks treatment with inhaled mannitol in subjects with cystic fibrosis. Previous studies with inhaled mannitol have demonstrated improvements in lung function, mucociliary…
1. Assessment of sensitivity of several outcome measures in muscle force and function in Duchenne muscular dystrophy2. Assessment of reproducability of different outcome measures3. Assessment of clinical relevance of measured change over time in…
Primary objectives1. To investigate prospectively the prevalence of cardiovascular damage due to cancer treatment and it*s change over time.2. To investigate markers of early and late toxicity of cardiovascular damage due to cardiotoxic treatment.…
1. Study of the incidence of TART in male CAH children in a multicentre setting 2. Detection of predisposing factors for tumour growth. 3. Evaluating of gonadal function in male CAH children with TART
Primary: To determine the pharmacokinetics of oseltamivir in children and in adults with significant co-morbiditiesSecondary: To examine whether the pharmacokinetics in our studied populations are comparable with the PK in other populations To…