3303 results
The aim of our study is to assess the prevalence of cardiac dysfunction and undiagnosed heart failure in women registered in general practice with a history of breast cancer who received chemotherapy and / or radiotherapy as compared to a matched…
Primary Objective: To determine minimum and non-provoking doses of soy protein (in mg) for soy allergic individuals Secondary Objective(s): To determine the relevant allergens of soy in soy allergy and to determine the relation between allergen…
The identify the health-related quality of life of elderly patients with resected stage III colon cancer and relate the outcomes to patient and treatment characteristics (surgery alone or surgery plus adjuvant chemotherapy). Furthermore, the impact…
The primary purpose of this study is to prospectively evaluate the accuracy of intra-articular glenohumeral injections via the posterior approach with (incipient) adhesiva capsulitis (frozen shoulder). Furthermore the confidence of the giver in a…
In this study the effect of the administration of NAC on the frequency and severity of pain and painful crises in daily life will be assessed as well as the related frequency and length of hospital admissions and health related quality of life. In…
To gain insight in mechanisms of case management and in succesful and less succesful aspects of case management in individual patient care. This leads to knowledge of potential added value of case management to regular care and (if there is added…
To determine the frequency of MBL and FCN SNPs in patients with a history of a proven gram-positive bacteremia, compared to patients without such history. A secondary objective is to determine whether extracorporeal circuits, used in cardiothoracic…
The family with the TRα2 premature stop enables us to investigate the biological role of the orphan wild-type TRα2 and the consequences of its dysfunction. The primary objectives of this proposal are (i) to search for a biological function of TRα2…
In this study we aim to investigate whether infusion of intestinal microbiota from lean (vegetarian) donors has differential effect on choline (d6-labeled choline) and carnitine (d3-labeled carnitine) metabolism and macrovascular inflammation (18F-…
Determination of post-traumatic osteoarthritis in patients with a short follow-up period after ankle-surgery.
The objective of this study is to evaluate if overload eccentric training on a flywheel ergometer, guided by a physiotherapist, is an appropriate training for athletes with patellar tendinopathy to reduce pain and a faster return to sport. The pain…
Main Objective: - to validate the identified cognitive profiles prospectively in a new population using confirmatory cluster analysisSecondary Objectives: - to identify the clinical and demographical factors associated to the identified cognitive…
The goal of this study is to find out which B-cell inhibitor results in the best reduction of anti A/B antibody levels at which time interval, to make the best choice for a particcular drug in the desensitization treatment in patients receiving an…
Primary objective: To assess the influence of the addition of rinsing with a 0.05% chlorhexidine-containing solution to usual daily oral hygiene care on the incidence of pneumonia in physically-impaired care home residents with dysphagia.Secondary…
Predicting fluid responsiveness during PLR and fluid challenge (FC) by changes in (Pms).
We aim to test the hypothesis that EndoCuff improves totaal number of adenomas detected and ADR compared with regular colonoscopy. In other words, we'll study if the Endocuff colonoscopy detects more polyps.
-To assess the central chemosensitivity by an carbon dioxide rebreathing test-To assess mouth occlusion pressures during the carbon dioxide rebreathing test-To study the relation between these results and the results obtained with the MRI and…
The study will evaluate the injection of AMDC for Urinary Sphincter Repair (USR) compared to a placebo dose, with the hypothesis that one or two treatments of AMDC is statistically superior to placebo at 12 months following the initial treatment.
The primary objective of the study is to assess whether ixekizumab 80 mg every 2 weeks (Q2W) or80 mg every 4 weeks (Q4W) is superior to placebo in the treatment of biologic disease-modifying antirheumatic drug (bDMARD)-naive patients with active…
The aim of this project is to develop a comprehensive EORTC questionnaire for assessing sexual health for male and female patients with cancer. Given the lack of a sexual health related measure that can be used in clinical trials and in clinical…