3303 results
Primary objective:To assess the two-year prevalence and incidence of clinical relevant arrhythmias in drug-resistant epilepsy.Secondary objective:To assess whether the recorded cardiac arrhythmias are related to epileptic seizures (subjectively from…
The purpose of this study is to demonstrate the effectiveness of renal denervation in lowering blood pressure in patients with therapy-resistant hypertension and end-stage renal disease who are on dialysis or who have a renal transplant.
Primary Objective: To identify variants in the humane genome that are associated with BE risk. Secondary Objective(s): We will collect information on BE length, complication of BE (dysplasia, ulcer, stricture or EAC), presence of esophagitis and…
In one FOA family we have detected a deleterious mutation in a compelling gene which co-segregates with the FOA phenotype in the family. This mutation is, therefore, is likely to be causal to the early onset OA. The objective of the study is:a) To…
Evaluation of long-term position, volume and FDG-uptake of the orchidopexied testis because of congenital undescended testis.
Primary Objective: the primary objective of this study is to determine the feasibility of [18F]FDHT PET/CT for in vivo evaluation of bone metastases in prostate cancer. Active locations will be compared with those seen on conventional imaging (bone…
Primary objective: To determine whether postoperative pericardial flush with a crystalloid can reduce postoperative blood loss by effectively removing contaminated pericardial blood after valvular surgery and correction for CHD. The primary…
To evaluate the benefit of Misoprostol prior to hysteroscopy in nulliparous and postmenopausal women regarding the reduction of pain
Primary objectives: 1. Does vitamin D supplementation improve depressive symptoms in older persons? 2. Does vitamin D supplementation improve physical performance and functional limitations in older persons?Secondary objectives: 3. Does vitamin D…
The aim of the present study is to validate a mobile measuring tool that is capable to determine the knee load during different daily activities.
Primary Objectives:- Evaluate changes in the immune system upon exposure to FVIII in patients with severe hemophilia A - Identify immunologic predictors of FVIII inhibitor development or tolerance
The overall aim of the DALI study is to identify the best available measures to prevent GDM in an ongoing pregnancy, to provide a cost-benefit calculation of GDM prevention for health care systems, and to establish a pan-European cohort of mother-…
Predicting fluid responsiveness during PLR and fluid challenge (FC) by changes in (Pms).
To investigate the (cost) effectiveness of early ACL reconstruction (<6 weeks after injury), compared to the usual timing of ACL reconstruction (> 3 months after injury). Hypotheis is that early ACL reconstruction results in less loss…
The objective of the current study is to determine whether the presence of donor-specific B cell memory determines whether a patient will develop graft rejection or inferior graft function, especially in kidney transplant recipients who have donor-…
The following research questions were formulated:• Does blood group P status (presence or absence of the 42C>T-SNP) correlate to GB3 content on fibroblasts and white blood cells of healthy controls?• Does blood group P status correlate to (…
The aim of this study is to evaluate androgen receptor (AR) and estrogen receptor (ER) expression non-invasively by means of PET imaging with the tracers 18F-FDHT and 18F-FES. To verify the PET results, the standard diagnostic biopsy will be…
The first objective to investigate is the pharmacokinetics of DP tobramycin using the Cyclops® at four different dosages. The other objective is the local tolerability of DP tobramycin using the Cyclops® at four different dosages.
This research project has 2 main goals and can therefore be divided into 2 parts: - The aim of part (A) is to qualitatively and quantitatively assess the daily-life experiences of CI-patients who do or do not wear a contralateral hearing aid.…
The aim of this study is to see if we can enhance the effectiveness of the nurse*s comforting capabilities through the addition of maternal scent communication during heellance.