3303 results
The main objective of this study is to determine whether tumor concentrations of kinase inhibitors at pharmacological active doses can be predicted from PET studies using tracer amounts (microdosing) of corresponding radiolabeled kinase inhibitors.…
The objective of this study is to evaluate efficacy and the safety of GelrinC® implant microfracture in the treatment of patients with symptomatic articular cartilage defect(s) of the femoral condyle.
1.1 To study whether and to what extent structured advance care planning for COPD patients can improve quality of end-of-life care communication. 1.2 To study whether and to what extent structured advance care planning for COPD patients can…
Rationale: The purpose of this project is to investigate the presence and course of natural WT1-specific and PRAME-specific immunity in EOC patients, with the intent to exploit the obtained knowledge of WT1-specific and PRAME-specific immunity for…
The overall aim of the study is to demonstrate that a comprehensive cardiac CT examination improves the diagnostic workup of stable chest pain in terms of accuracy, efficiency and costs. In concrete terms, the purpose of this randomized controlled…
The primary outcome measure will be comparison of improvement in endurance of a work rate initially eliciting exercise limitation after 6 minutes (calculated from the power-duration relationship before and after training). We will also compare…
I) Is the infusion of crystalloid fluids in healthy subjects associated with a reduction in microcirculatory perfused vessel density and increase in perfused boundary region? II) Does colloid administration attenuates the crystalloid-induced…
This study investigate the problems which patients experience after hospital discharge after TKA surgery during the first six weeks post-operative. We will use the outcome of this study to optimize the first six weeks after hospital discharge.The…
To examine the 1- and 3-year prognostic value of the CAR-test in patients with peripheral artery disease regarding the occurrence of vascular complications and the progression of PAD
The objectives of this follow-up/extension study of the VIPES study are:• To assess the efficacy of Viaskin® Peanut after up to 36 months of Epicutaneous Immunotherapy (EPIT) in peanut-allergic subjects.• To evaluate the safety of long-term…
The aim of the study is to assess physical fitness of people in rehabilitation after lower limb amputation and to assess their physical strain during the regular rehabilitation program and specific (physical therapy) sessions of this program.…
To evaluate the effectiveness, cost-effectiveness and quality of life of Flaminal® versus Flammazine® in the treatment of superficial and deep partial thickness burns.
Please refer to protocol, section 1.2 "Rationale"
Primary objective:To determine sAF levels in children and young adults with T1DM and in children with obesity with or without T2DM and determine the correlation between sAF levels and HbA1c in children and young adults with T1DM and in children with…
The aim of this study is to investigate immune response to pneumococcal vaccination in patients after community acquired pneumonia with S. pneumoniae compared to pneumonia patients with another pathogen.
Primary objective is to assess the reliability and assess the reliability and construct validity of the Repetitive Movement Test (RMT) as a measure of spasticity in children with CP scheduled for ITB treatment, between 6-18 year.
- The primary objective of this proposal is to assess the intraindividual reliability of PAS TMS, Theta-burst rTMS and ppTMS indices as measures of neural plasticity and cortical inhibition, by performing test-retest measurements separated by a…
To investigate the hypothesis that women with uterine prolapse stage 2 or more treated by laparoscopic sacrohysteropexy will have equal or lower recurrence rate of prolapse compared to women treated by vaginal sacrospinous hysteropexy.
- To study the clinical characteristics and disease course of patients with LEMS with or without SCLC- To identify the characteristics of the humoral or cellular immune response that are associated with the prolonged survival of patients with SCLC…
Our first goal is collecting high quality raw EEG waves, - measured simultaneously on multiple locations of the brain - during a pharmacological reproducible anesthesia. The goal is to observe EEG patterns that allow the development of technology to…