21 results
The study comprises 2 parts.Part 1: Primary: to assess sexual functioning, sexual self image and psychological and relational functioning in MRKH women with surgical or non- surgical created neovaginas and their partners and make a comparison with…
The objective of this study is to investigate whether the differences in DNA methylation between individuals who were exposed in utero to the Dutch Hungerwinter (F1) and their non-exposed, same-sex siblings (F1) - as identified in epigenome-wide…
The objective of the study is to determine hypothalamic function in response to oral glucose ingestion in obese subjects.
The main objective of this prospective randomized study is to examine the effect of low-dose radiotherapy on pain sensation in patients with early OA of the hip. Our hypothesis is that radiotherapy can achieve a pain-reducing effect of at least 20%…
SARS-CoV-2 is present in the cerebrospinal fluid of COVID-19 patients with acute respiratory failure
It is hypothesized that the FitMáx© questionnaire is a valid clinical assessment tool for CRF compared to the gold standard, a cardiopulmonary exercise test. Moreover we believe the FitMáx© to be fairly accurate in the preoperative risk assessment…
We hypothesize that FMT from a healthy donor will modulate the microbiome of the pouch of patients with ulcerative colitis, and will thereby resolve the inflammation of the pouch.
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
"The objective of this study is to evaluate the feasibility and effectiveness of a nursing nutrition intervention (Nurses for Food) on malnutrition in hospital. The intervention will be developed according to the Britisch Medical Research…
Predominantly sleeping in the non-supine position could improve oxygenation and thereby shorten the disease course in admitted COVID-19 patients.
to further evaluate and monitor the safety and performance of the “BasIQ-4®” in a population of women delivering in general hospitals in The Netherlands when used as intended
The aim of this study is to assess the predictive value of the HowRwe questionnaire in relation to the EUROPEP questionnaire by analyzing scores acquired in Dutch GP practices. We expect that high HowRwe scores are associated with an positive…
A cesarean section performed without a clear indication results in additional morbidity and costs without improvement of outcome. The group of women delivering their first baby in cephalic presentation at term is the largest contributor to the…
The size of intrinsic foot muscles is associated with gait biomechanics and balance in older adults
Hypothesis 1: Participants who receive either of two CBM interventions will reduce their gambling more than participants completing the placebo intervention immediately after the re-training (post-intervention assessment) and by the 3-and 6-month…
The aim of the study is to gather information regarding COVID-19 infections during pregnancy. Up to now, little is known about COVID-19 during pregnancy.
Primary objective:Does addition of azithromycin to standard chloroquine treatment result in a higher clinical cure rate at day 7 than treatment with chloroquine alone in patients with COVID-19.Cure is considered when 4 criteria are present:(1) O2…
The objective of this study is to establish the safety and effectiveness of a dual epicardial and endocardial ablation procedure for patients presentingwith Persistent Atrial Fibrillation or Longstanding Persistent Atrial Fibrillation utilizing the…
The aim of this study is to identify whether it is possible to safely discontinue treatment in stable RRMS patients who have shown no evidence of active inflammation in the years prior to inclusion in terms of the return of inflammatory disease…