3397 results
This study has been transitioned to CTIS with ID 2023-508897-27-00 check the CTIS register for the current data. Primary:• To compare the efficacy of elranatamab vs lenalidomide Secondary:- To compare the efficacy of elranatamab vs lenalidomide- To…
This study has been transitioned to CTIS with ID 2024-511235-10-00 check the CTIS register for the current data. To establish one of three study arms, R-CHOP/R-DHAP followed by ASCT (control arm A), R-CHOP + ibrutinib / R-DHAP followed by ASCT and…
Possibly, outcomes of treatment can be further improved by adding atezolizumab to neoadjuvant chemoradiation. As a first step we aim to know whether the addition of atezolizumab feasible. That is, we want to know how the treatment is tolerated and…
To set up a trial*ready cohort by bringing together 7 European cohorts and 1 US cohortand include new subjects, which together comprise more than 800 subjects with the developmentand validation of innovative assessment instruments and disease…
The purpose of this study is to demonstrate the impact on progression of structural damage in the spine as measured by the mSASSS in patients with AS. Data from this study will be used to support the submission of an AS label extension to include a…
This project will be subdivided into three sections:Part I. Comparison of the ESM vs. SR-BDs and other retrospective questionnaires in the assessment of urological complaints in OAB such as urgency. Part II. Validation of new patient-reported…
To identify prognostic factors for disease course and severity, as soluble and cellular biomarkers, immunological, genetic, radiological and demographics factors.
This study has been transitioned to CTIS with ID 2024-518215-18-00 check the CTIS register for the current data. To explore safety, tolerability and efficacy of avalglucosidase alfa in previously treated alglucosidase alfa late-onset Pompe disease…
This study has been transitioned to CTIS with ID 2024-517700-12-00 check the CTIS register for the current data. To improve disease-free survival in patients with high-risk rectal cancer by treating these patients with adjuvant chemotherapy in case…
The primary objective of this study is to implement a transmural patient care pathway as recommended by the EASL guideline of June 2024, in order to identify patients with MASLD and its progressive form of MASH in primary care centres (PCC) and…
To evaluate the influence of DSA monitoring, provided by the NarcotrendTM monitor, on the speed of emergence and recovery from GA.
This study has been transitioned to CTIS with ID 2024-518304-53-00 check the CTIS register for the current data. The primary objective of the study is to compare the PFS of SPd versus EloPd in patients with MM who have received 1 to 4 prior anti-MM…
To identify potential rehabilitation needs of adult patients with burns we aim to:1) investigate the course of physical fitness, physical activity and fatigue after discharge. 2) identify factors that can predict the recovery, or lack thereof, at an…
To investigate:Study 1. the influence of graft choice (hamstring v.s. quadriceps v.s. patellar tendon v.s. VKB repair) for ACLR on dynamic tibiofemoralmovements after an ACLR;Study 2. the influence of the anatomy of the knee on dynamic tibiofemoral…
In this study, we aim to identify the diagnostic value of indocyanine green (ICG) fluorescence imaging for SLNBs via the mastectomy incision.
First-In-Human Clinical Investigation to evaluate the safety and performance of the Adagio Medical PFA and PFCA Systems in the ablation treatment of symptomatic Persistent Atrial Fibrillation (PsAF).
Primary Objective:- To assess oral health in patients with memory complaints visiting a memory clinic. Oral health is defined for this study as the presence of deep caries lesions, periodontal pockets >6 mm, swollen and red gums, chewing…