306 results
The aim of this proposal is threefold: (i) test a neuroscientific model of prosocial development by relating neuroscience discoveries to changes in several dimensions of prosocial development in a comprehensive study including children, adolescents…
In this study, the aim is to perform a clinical evaluation of the NovioMini in children during behavioural bladder training to examine the performance of the NovioMini as a full-bladder-based notification system during natural bladder filling.
The randomized controlled trial (RCT) will be performed at Karakter Child and Adolescent*s Psychiatric Hospital and will be implemented at all locations, spread out over three provinces in The Netherlands. The project aims:1. To explore the…
To establish a healthy control group for microcirculatory parameters for current and future studies on the paediatric microcirculation.
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
REE will be assessed using indirect calorimetry. Oxygen consumption (VO₂) and carbon dioxide production (VCO₂) will be measured. The respiratory quotient (RQ) will be derived from VO₂ and VCO₂. Body composition will be determined by…
The objectives are firstly that Love is... promotes the healthy sexual development by increasing knowledge and positive attitudes towards sexuality. Secondly, characteristics of adolescents who do not improve from the general prevention program are…
Smell and taste function change during chemotherapy consequently affecting 1) dietary intake 2) eating behavior 3) anthropometry 4) quality of life
The standard-of-care sentinel lymph node (SLN) procedure in paediatric cancer patients consists of a preoperative intradermal injection with 99mTechnetium-nanocolloid as radiotracer in combination with an intraoperative injection of blue dye for…
Primary goal:To provide an overview of long term effects (neurocognitive, behavioral and learning problems) in children with MTHI and to identify specific risk groups with a higher prevalence of more serious problems. This knowledge can contribute…
To gain insight into the biological pathways that are influenced by the CEEx30/31 mutations.
The PowerMe study will analyse fatigue characteristics and severity in children and adolescents with mitochondrial myopathy and their families. Then a blended personalized cognitive behaviour therapy program for fatigue will be designed and tested,…
This pilot prospective cohort study is designed to provide feasibility data for a large global study that will critically evaluate the impact of sport activity and FAI development during the critical phase of hip maturation.Primary Feasibility…
1.3. Study Design Rationale The ATLAS-INH trial (ALN-AT3SC-003) is a multicenter, multinational, randomized, openlabel Phase 3 study designed to demonstrate the efficacy and safety of fitusiran in patients with haemophilia A or B with inhibitory…
This study aims to gain clarity on the issue of treatment for clinical levels of social anxiety in adolescents by testing the effectiveness of a group-based intervention. Most importantly, it aims to research the effectiveness of an added mHealth…
1. Inventory of the current care of boys/men with Duchenne Muscular Dystrophy in the Netherlands: To establish the extent of implementation of the international guidelines and its updates in the Netherlands and to explore the relationship between…
Primary Objective: Our overall aim is to improve selection of patients for epilepsy surgery and predict surgical candidacy with use of genetic test results as a biomarker. The specific objectivesare:Cohort I1. Apply genetic testing for epilepsy gene…
To examine the feasibility and acceptability, and preliminary efficacy, of a new developed enhanced CBT (eCBT) for pediatric obsessive-compulsive disorder
To validate and assess the impact of the use of the MyCyFAPP system for self-management in children with CF, more specifically the effect on patients* quality of life, nutritional status, gastro-intestinal symptoms, general wellbeing and economic…
In a randomised setting we want to investigate wheter we can reduce anxiety and pain in children that need an IV catheter by using a 360 Virtual Reality video in preparation of the actual needle placement.