2920 results
To demonstrate that novel MEG sensors can be used successfully in clinical practice, and to demonstrate their effectiveness as a powerful diagnostic tool in epilepsy.
The first goal is to test whether the temporary disruption of the right TPJ leads to changes in the functional connectivity between brain areas that are related to body awareness.Second, the study intends to test how temporary inhibition of the TPJ…
The main objective in this study is whether biofeedback on the psychofysiological stress level is effective in reducing incidents in youth in residential care.
Prevalence of CeD is about 15 around the world with a variation from 1:100 to 1:300 in different geographical areas [2, 3]. The diagnosis is made out of case finding among at-risk population such as diarrhea, anemia, ibs-like abdominal complaints,…
The primary objective is to investigate if models are able to predict changes in blood glucose levels in patients with T2DM when small changes in dietary intake and/or physical activity are applied.
Main objective: To determine the effects of age and surface inclination on muscle activation during positive and negative joint work.Secondary objective: To determine if walking on an inclined surface magnifies age-differences in muscle activation…
To examine the OcuDrive test package in glaucoma patients and healthy controls in relation to fitness to drive. The main objective is to find the tests from the package that discriminate best between fit and unfit drivers.
Part A: Determine safety and tolerability of FTX-1821 in healthy subjects. Part B and C: Determine safety and tolerability of FTX-1821 in FSHD patients.
The key objective of the study is to assess the validity of a quantitative uniform examination technique for estimating physiological properties in MND patients, to better examine the neuromuscular properties from which defective motor behavior…
Primary objective1. To compare the Area under the curve (AUC) of endoxifen in patients with breast cancer treated with tamoxifen with and without diclofenac.Secondary objectives1. To compare the Area under the Curve (AUC) of tamoxifen and endoxifen-…
Gaining an objective insight in muscle fatigue during exercise for patients with NMD by1. comparing the timing of change in sEMG amplitude and sEMG median frequency, to gas exchange variables, heart rate, work load, muscle strength, muscular…
The main goal of this study is to analyse NK cell phenotype in women with unexplained recurrent miscarriage in relation to their physical health.
The purpose of this research is to investigate whether treatment with nicotinamide riboside (vitamine B3) has a positive effect on the disease course of patients with ataxia telangiectasia.
Objective(s)* To investigate the pharmacokinetic behaviour of a single dose of MMF;o Plasma concentrationso Cellular concentrationso Relationship between plasma and cellular concentrations* To investigate the pharmacodynamic effects of a single dose…
(1) Study consequences of prenatal undernutrition for cognitive function and brain parameters in older age; (2) Study consequences of prenatal undernutrition for age-related changes in cognitive function and brain parameters; (3) Study DNA…
This pilot study aims to explore whether and why the cardiorespiratory fitness is compromised in newly diagnosed patients with early Relapsing Remitting Multiple Sclerosis (RRMS) with no or minimal clinical symptoms (i.e. Expanded Disability Status…
To determine the test-retest variability of Compass perimetry at the edges of glaucomatous scotomas and compare it with the Humphrey Field Analyzer.
The aim of this randomised crossover trial is to compare the Manometric TMC brace with conventional plaster braces in terms of patient satisfaction, pain, hand function, compliance and patient preference.
Primary (Part A)To evaluate safety and tolerability of LY3526318 in healthy participants following a single oral dosePrimary (Part B)To evaluate safety and tolerability of LY3526318 in healthy participants following multiple once-daily oral doses…
To evaluate the safety and efficacy of ravagalimab vs placebo for the treatment of primary Sjogren's syndrome (pSS) in subjects with moderately to severely active primary Sjogren's syndrome (pSS).