791 results
In this trial we will study the utility of PerfusiX-Imaging for the identification of intersegmental planes during thoracoscopic segmentectomy.
Primary objective To investigate the therapeutic potential of A. soehngenii and pasteurized A. muciniphila combined with B. animalis subsp. lactis and FOS with and without conditioned vegan LFMT capsules to reduce NASH in patients with fibrotic NASH…
To evaluate the effect of diuretics on volumes and function of the right heart in pulmonary hypertension patients.
This study has been transitioned to CTIS with ID 2023-507041-28-00 check the CTIS register for the current data. The primary objectives of this study are to:• Evaluate the incidence and severity of late-onset targeted adverse events (AEs)/serious…
Main objectiveThe primary objective of this study is to assess whether a higher HRQoL, in terms of impact of the disease and its treatment on physical and role functioning, is achieved with metronomic schedules of doxorubicin or cyclophosphamide…
Het primaire doel is het bepalen van de sensitiviteit en specificiteit van de MR Pulmonalis Angiografie (MRPA) waarbij de CT Pulmonalis Angiografie (CTPA) de gouden standaard is.** Als secundaire uitkomsten: het bepalen wat de klinische…
The main objective of this study is to evaluate the feasibility of the Viamigo intervention among people with dementia living in the community and their informal caregivers. The secondary objective of this study is to assess the first responses of…
The primary objectives of COMPANION study 2 are to determine the acceptability of the couple intervention and the potential effectiveness for patient fatigue. Secondary objectives are to examine the feasibility of trial procedures and the potential…
Our main goal is to develop an in vitro model to investigate the function of wildtype and mutant KDM2B in neuronal development. We want to use this model to investigate genotype-phenotype correlations, elucidate isoform expression in neuronal…
The primary objective of DRAGON 2 is to demonstrate the superiority of combined PVE/HVE over PVE alone in either the resectability of the patients within 3 weeks after intervention defined as FLR sufficient for resection on week 3 and the 5-year…
PrimaryThe primary objective of this study is to assess the safety and tolerability of BEN2293, administered as multiple topical doses to increasing body surface area (BSA), in patients with mild to moderate AD.SecondaryPharmacokinetics· To…
The objective of the study is to assess the efficacy and costeffectiveness of eCAR in patients with MALS.
Primary Objective: Can VR reduce periprocedural and postprocedural pain during reduction of fractures and joint dislocations in the ED? Secondary Objectives: What are the effects of VR on peri-procedural anxiety?Does the level of peri-procedural…
Primary objective: To evaluate the safety and tolerability of single ascending i.v. doses of OMN6 in healthy young and elderly adult subjects.Secondary objective: To evaluate OMN6 PK in plasma following single ascending i.v. doses in healthy young…
The aim of the here proposed study (BLOC-II) is to clarify whether cardiac function in survivors of BC should be monitored by GPs. We expect to clarify whether an unselected population of long-term BC survivors is at increased risk of developing…
To investigate the tolerability and effect of pure cafeine food suplement pre-administration on myocardial [18F]FDG uptake suppression.
Evaluate the performance and safety of HASS 200 (HARMONY AORTIC STIMULATION SYSTEM) in treatment of heart failure subjects.
This study aims to determine feasibility of providing and following ICU discharged patient with smart technology for 3 months after hospital discharge from a general ward of the Leiden University Medical Centre. If proven successful, home monitoring…
We aim to further explore the role of decreased activity and stability of PK in several types of hereditary hemolytic anemia and non-regenerative anemia. Moreover, we will study the effect of restoring this instability using second generation (…
Determine the kinetics of fructose metabolism and its role as a metabolic substrate following a high vs low fructose diet in subjects of SAS or Caucasian ethnicity.