430 results
Primary objectives: 1.1) To investigate to what extent the different functions of the cerebral microvasculature are impaired in type 1 diabetes; and 1.2) To investigate to what extent the different functions of the cerebral microvasculature are…
The overall aim of this project is to unravel the role of IFN-I in ILD in the known/classified SADs and in ILD with autoimmune features but without a specific SAD diagnosis (IPAF), with as ultimate goal better treatment. Since 13-40% of ILD patients…
To evaluate the degree of osteoarthritis 5 to 10 years after a hip arthroscopy in comparison with the non-operative side.
To determine the effect of accelerated pacing (lower programmed rate of 80 bpm) compared to pacing at the standard programmed rate of 60 bpm on HRQoL in symptomatic AF patients undergo-ing pace-and-ablate strategy with LBBAP.Secondary objectives: -…
To assess whether adjuvant chemotherapy can be safely omitted in patients with pathological stage I (pT1a/b/cN0) TNBC and a high sTIL score (defined as >=50% for patients <40 years at the time of TNBC diagnosis; >=75% for…
The aim of this fundamental research is to optimize methods and to investigate the effects of different variables in the human body on the clot structure, contributing to the knowledge of blood clotting, cardiovascular disease, and bleeding…
We aim to characterize innate anti-viral defence responses in the upper airways of COPD patients.
The primary objectives are to investigate in older adults the effect of 16-week wild blueberry consumption on (regional) vascular function and insulin-sensitivity in the brain, while we will also focus on changes in cognitive performance as assessed…
To evaluate the long term functional and radiological effects of surgical treatment of Weber type C (AO 44-C1/2/3) fibular fractures
To use the CE-marked CLAUDENTIFY®6 IHC-Assay as a pre-screening test to determine Claudin 6 protein expression in patients with histological or cytological documentation of a solid tumor that is metastatic or unresectable provided as a pathology…
The primary objective of this study is to evaluate the change in HbA1c from start of intervention (baseline of the core study) to post-four months of ketogenic diet compared to standard of care (core study) in patients developing pasireotide-induced…
The objective of the SEAL Early Feasibility Study (STUDY) is to provide proof of concept and initialclinical safety data for the Aortoseal Endostapling System for the fixation and seal of abdominal aorticaneurysms (AAA) endovascular grafts to the…
This clinical performance study will evaluate the effectiveness of the CLDN18.2 (SP455) Clinical Trial Assay in identifying CLDN18.2 status in Adult Participants with Advanced or Metastatic Solid Tumours treated with AZD5863.
Zie onderzoeksprotocol.
Primary Objective: To determine the difference in change in sputum viscoelasticity on HME and HFTO during disconnection sessions from the ventilator in tracheotomised patients. Secondary Objective(s): 1. To determine the difference in respiratory…
To compare the use of mitoPO2 with the use of conventional markers in guiding interventions to treat shock in patients undergoing cardiac surgery
Primary objective:i. Investigate cerebrospinal fluid (CSF) polyol concentrations in patients following traumatic brain injurySecondary objectives:i. Investigate the association between plasma glucose, CSF glucose and CSF polyols following traumatic…
To analyse complications due to primary percutaneous stenting in patients with resectable pCCA.
Transiently improve episodic memory in early AD patients with precuneal gamma (40 Hz) tACS (main objective) and identify what functional brain activity/network changes underlie this memory improvement (secondary objective)
Primary Objective:Our overall aim is to develop an easy-to-use, and interpretive method for the early detection of valvular heart disease and thoracic aortic aneurysm based on arterial blood pressure waveforms, collected non-invasively. Therefore,…