98 results
Main objective: Develop a protocol to reproducibly infect mosquitoes with blood from human study participants undergoing asexual blood stage CHMI with the P. vivax clone PvW1.Secondary objectives: Maximize mosquito infection rate with PvW1 by I)…
Primary objective* To determine the extent to which muscle strength is affected in patients with RYR1-RM with autosomal dominantmutations and describe measurements over time.Secondary objectives* To determine the extent to which fatigue and…
Unravelling the *measles paradox* by in-depth characterization of the immune repertoire before and after natural measles or measles vaccination.
The objective of the SEAL Early Feasibility Study (STUDY) is to provide proof of concept and initialclinical safety data for the Aortoseal Endostapling System for the fixation and seal of abdominal aorticaneurysms (AAA) endovascular grafts to the…
Zie onderzoeksprotocol.
To identify the effect of psoriasis and the treatment with biologics on the pre-pregnancy uterine immune environment of psoriasis patients.
The purpose of this protocol amendment is to meet the current and future needs of the MacTel Project’s collaborating investigators and continue meeting initial objectives. In addition, a third objective is to understand the mechanisms involved in…
The aim of this study is to describe the scar quality in a paediatric burn population treated with Glyaderm up to 12 months after surgery.
In this explorative study, we aim to: Analyze neoantigens expressed on different tumors of CMMRD patients, to identify more possible target antigens for DC vaccination studies and to select the antigens that are most frequent. …
This project aims to improve physical performance in older patients, by offering a personalized combined nutritional intervention with a physical activity training program. The intervention starts at hospita! admittance, and is continued after…
The objective of this study is to pilot the feasibility of MRI and cine imaging in improving pre-operative staging of colon tumors. The specific aims of this pilot study are to establish an optimized scanning protocol and provide preliminary…
We want to remap the entire bacterial ecosystem in the gastrointestinal tract of patients with lgA nephropathy after a period of roughy two years, in order to gain insight into the processes that may play a role in the development and progression…
This mixed-methods pilot study will explore the effects of a group-based MBI on body and emotional awareness in TGD individuals by collecting both quantitative measures and qualitative experiences on an adapted gender-inclusive MBI program.&…
This study aims to evaluate A-mode ultrasound for assessing JVPW characteristics as a non-invasive tool to discriminate between healthy subjects and those with pulmonary arterial hypertension patients, and to assess if JVPW changes relate to…
Primary ObjectiveTo assess the safety, feasibility and frequency of relapsing P. vivax PvW1 infection after experimental sporozoite-administered Controlled Human Malaria Infection (CHMI)Secondary ObjectivesTo assess the immune response to primary…
Generation R studies growth, development and health from early pregnancy into adulthood. The study aims to contribute to the development of strategies for optimising health and health care across the full life course.
Generation R Next aims to examine the influence of preconception and pregnancy factors on growth, development and health of children from the earliest phase of life into young adulthood. The study aims to contribute to the development of strategies…
The primary objective of this project is to evaluate the differences between a wide variety of cardiac disease and healthy volunteers using novel echocardiographic techniques (LV SV-loops, 3D RV beutels and SWI) and relate these to patient…