511 results
To assess the long-term safety and tolerability (and in particular the infection occurrence) ofACZ885 in patients with rheumatoid arthritis (RA) who participated in the core CACZ885A2204,CACZ885A2206, or CACZ885A2207 studies.
Bevacizumab, Radiotherapy and Temozolomide Safety study in biopsied or resected primary GBM patients
Primary objective is determination of safety of combination of standard treatment with 3 bevacizumab infusions, followed by the standard adjuvant cycles of temozolomide. Secondary objectives: determination of: efficacy, classical response end-points…
The aim of this study is to test the hypothesis that intravenous acetaminophen will reduce morphine requirements in postoperative infants significantly (>30%).
1)To assess the preliminary pharmacokinetics of [14C]-Org 201745, [14C] Org 244378 and [14C] Org 245021 when administered as a sub-therapeutic dose by the oral route to healthy post-menopausal female volunteers.2) To evaluate the safety and…
The aim of this study is to determine whether the treatment is effective in reducing symptoms in patients suffering from AVH*s.
To compare the efficacy of the L300 with a conventional AFO or orthopedic shoes with regard to walking capacity in stroke patients suffering from a drop foot.
Evaluation of provisional T stenting using a bare metal stent in combination with a paclitaxel eluting balloon compared with a normal balloon. And comparing a bare metal stent in combination with a paclitaxel eluting balloon with a paclitaxel elutin…
The study is performed in order to develop a population pharmacokinetic and pharmacodynamic model of Propofol when used for induction and maintenance of anaesthesia in the morbidly obese patient (BMI > 40). A covariate analysis will be…
This research has the goal to determine which treatment is the most effective treatment in terms of prevention of treatment failure, in costs and has the patients preference when comparing PDT, Imiquimod and 5FU.
The objective of this study is to examine whether the FTC-intervention improves the quality of pharmacotherapy in individual patients.
To assess the effects of dexamphetamine with and without alcohol on simulated driving performance.
Primary : to investigate the safety, tolerability and antiviral activity of multiple oral doses of JTK-652 administered for 4 weeks in subjects with chronic hepatitis C infection (genotype 1a, 1b)Secondary : to investigate the pharmacokinetics of…
The objective of this study is to compare the bioavailability of 100 and 200 mg pills that are produced in different ways: coated or non-coated. Bioavailability means the amount of medication which is available for use in the body. In this study the…
Het doel van de studie is het vaststellen van de incidentie van diep veneuze trombose na voorste kruisbandreconstructie bij patiënten die geen trombose profylaxe krijgen, middels een bilaterale uitgebreide compressie echo duplex.
In this research study the role of context in extinction will be investigated in healthy adults in a laboratory setting. Renewal of fear will be compared in two contexts of different modality: a visual context (the illumination of the room) and an…
In the third follow-up we will include both factory A and B. The mayor strength is the increase in power by addition of approximately 15 years of follow-up. We will investigate the association between exposure and mortality, cancer mortality and…
zie Nederlandse samenvatting
This current study aims to investigate the use of bèta-TCP, a synthetic tricalcium phosphate, as a filler of the autologous symphyseal bone graft harvest site in patients undergoing grafting of clefts of lip, alveolus and palate.The specific…
Zie onderzoeksprotocol
To compare the effect of amiloride on lithium-induced Nephrogenic Diabetes Insipidus with the effect of hydrochlorothiazide, measured as urine volume and maximal urine osmolality.