297 results
The aim of this study is to determine the time of incidence of TBI, by measuring the concentration of the biomarkers in CSDH and to investigate which method can be applied to determine the age of CSDH with hemoglobin derivatives.
Primary Objective: To study the options of the PulmoVista 500 system to visualize regional real-time lung ventilation in healthy volunteersResearch questions:- Can the PulmoVista 500 system provide sufficient information regarding regional lung…
The pilot study has three main objectives: 1) To determine the exposure to gluten in celiac patients on a gluten free diet and the variance within this exposure; 2) To determine the gluten content of gluten free- labelled products commonly used by…
Primary Objective: to determine the strength of the dynamic autoregulation of patients after cardiac arrest during the post cardiac arrest syndrome. Secondary Objectives:to observe the natural course of the autoregulation during the first year after…
The main objective of the study is to determine the diagnostic and prognostic added value of careful history taking and Nexfin in the initial evaluation of (pre-) syncope patients in the ED and the follow-up period. The secondary objective is to…
Evaluate the differences in the three CT techniques, concerning differences in target volume, dose differences and feasibility. This study will result in an advice which CT technique should be used in the near future, in order to treat the stage I/…
Determine the repeatability, inter and intra-observer variability of the *Scolibed*. Determine the variation in stiffness for healthy individuals and for scoliotic patients. Compare the results of healthy individuals and scoliotic patients.
The primary objective is to investigate the influence of vigilance state on MEP amplitude in healthy adults. Secondary objectives are to develop a paradigm to stabilize vigilance state resulting in lower MEP amplitude variability in healthy adults…
The aim of this study is to test the feasibility of a GXTT, combined with a SET in adults with ID, through completion rate of the GXTT and the SET, the subjective experience of the participants and determining if the VO2peak of the SET is likely to…
In the current study a normal reference value for cTn-I in blood from healthy adults will be determined and will be measured with the new device. This reference range is age-dependent. To measure the normal values per age group, blood samples will…
To assess reliability and responsiveness of the IMP in PPT practise. IMP*s responsiveness will be compared to that of the AIMS. .
The primary objective of the present study is to assess the feasibility and safety of a newly developed PET-guided breast biopsy system in breast cancer patients.
To validate two novel genomic biomarkers that provide information with respect to the presence of PCa, disease aggressiveness, and progression towards recurrent and metastatic disease.
Primary objectiveTo evaluate the efficacy of low dose intravenously lidocaine in comparison with placebo in terms of pain relief after the first oxaliplatin administration measured by a numeric rating scale (NRS 0-10).Secondary objectives1.…
Primary objective * To determine the maximum tolerated dose and recommended dose of metformin plus chloroquine in patients with IDH1/2MT glioma, IHCC and CS Secondary objectives * To describe the toxic effects of metformin plus chloroquine in…
To validate and compare smartphone-connected blood pressure monitors produced by Withings, Qardio and iHealth with the gold standard and a validated automatic blood pressure monitor.
The primary objective of the study is to investigate attentional disengagement from both itch and pain in healthy subjects. The role of individual characteristics in attentional disengagement from itch and pain will be explored.
Primary Objective: To demonstrate the safety and efficacy of an OCT guided strategy for stent implantation.Trial Hypothesis: OCT-guided stent placement with application of a novel algorithm is non-inferior to IVUS-guided stent placement and superior…
The aim of this study is to image and model patient specific ACL-deficient knees applying several developed methods, to determine the feasibility of PKTD and MRI based FE models in assessing knee laxity in ACL-deficient knees before and after…
To make MRI suitable for an MRI-only workflow for magnetic resonance (MR)-guided (MR-linac) stereotactic radiotherapy for localized RCC. The objective of the current study will be MRI-sequence optimisation. Sequences will be optimized for MR-based…