50 results
Primary Objective: Does DBS result in cognitive changes in patients with OCD on the long term? Secondary Objective(s): Does DBS result in personality changes in patients with OCD on the long term?Are certain cognitive profiles associated with…
To investigate the effect of whey and casein ratio of IFT on intragastric behavior, gastric emptying and postprandial plasma metabolome
To assess whether co-ingesting keto-analogues of branched-chain AAs along with protein during HD can attenuate HD-initiated muscle catabolism.
Primary Objective: To quantify the variation in post-prandial plasma AA profiles between (and within) individuals after consumption of a poorly digestible plant protein source (lucerne). Secondary Objective: To compare the variation in postprandial…
To assess the impact of protein in a solid (bar) and liquid (drink) form on post-prandial amino acid responses in vivo in healthy young women.
The primary objective is to determine if there is a difference in autonomic function between patients with Alzheimer*s disease (MCI and AD) and a matched control group. The secondary objectives will be explorative and aimed to investigate…
The objective of this exploratory trial is to explore the acute and chronic effects of daily olive leaf extract supplementation on muscle energy and fatigue in healthy male adults
To study the effect of individual control of the light on thermal comfort
To contribute to the evaluation of 'fasting mimicking diet' application in oncotherapeutic setting and to gain insight on the underlying mechanisms in response to a fasting mimicking diet. This explorative study focuses on the immune…
To examine the thermophysiological responses to prolonged exercise in hot and humid environmental conditions in patients with a history of exertional heat stroke or malignant hyperthermia susceptibility and compare the thermophysiological responses…
The objective of this proof-of-concept study is to investigate (differences in) small intestine microbiota and postprandial glycemic responses.
Obtain phased-contrast 4D flow MRI scans in 20 healthy volunteers to quantify local blood flow in the thoracic and abdominal aorta and extract boundary conditions for future in vitro studies. Furthermore, the 3D geometry of the vessels within…
To compare the post-prandial muscle protein synthetic response following ingestion of a whole-food meal containing meat versus the ingestion of a meal containing only plant-based protein sources in vivo in healthy, older men and women.
We here validate the algorithms for movement analysis that were developed previously in healthy participants (METc 2019.542; regarding quantitative aspects of movement) and that were derived from a review of the literature (regarding qualitative…
Primary Objectives* To investigate the intra-variability (day-to-day) of glucocerebrosidase pathway biomarkers in HV, PD-GBA+ and PD-GBA-Secondary Objectives* To investigate the intra-variability (within-day) of glucocerebrosidase pathway biomarkers…
To assess the effect of Virtual Reality mediated visual and auditory lowering of electrical pain detection and tolerance thresholds
* To assess effect of zolpidem compared to placebo on walking (adapt)ability in healthy elderly as measured by the Interactive Walkway. * To assess effect of suvorexant compared to placebo on walking (adapt)ability in healthy elderly as measured by…
The objectiveof this study is to evaluate the short term clinical applicability of the Provox Vega HP and to investigate its potential limitations and benefits. As a result of the evaluations, the design could be adapted to arrive at the optimal…
Our primary objective is to replicate two experiments conducted by Fomenko and colleagues (2020), the first investigating whether TUS over M1 decreases excitability, and the second investigating whether varying TUS sonication duration significantly…
Primary objectives: - To collect raw measurement data of the urinary bladder region of volunteers with the early prototype of the Bladder Sensor in multiple postural positions to evaluate the detectability of the bladder in the intended users - To…