3650 results
The main objective of this specific study is to examine to what extend differences in cognitive functioning between people are due to complex interactions between genes and environment.
To evaluate the efficacy of ROLL versus WGL in breast conserving surgery for non-palpable breast cancer.
This study aims to identify the relationship between candidate genes such as for instance BDNF, 5-HTTLPR, DAOA, G72, DTNBP1, NRG1 and COMT with cognitive function and emotional- and behavioural traits.
The prime objective of the proposed study is to apply treatment modeling for superficial hyperthermia in a well-defined group of patients to investigate the potential of predicted 3-dimensional energy as source for a dose parameter that is…
The main objective is to study pregnancy rates after using metabolomic profiling added to the selection of viable embryos by morphology, compared to using only morphology.
The main objective of the study is a head tot head comparison of the everolimus coated XIENCE-V* stent with the paclitaxel coated TAXUS* stent in order to observe whether there is a difference in clinical outcome between both stents. Efficacy of…
The study is divided in two parts. In the first part, we will study our hypothesis that the biological activity of antiangiogenic therapy is partly mediated by inhibition of platelets. We will study whether antiangiogenic agents inhibit the…
Primary aim: To investigate whether PET-CT (using [18F]FDG, [18F]Fluoride and [11C]PK11195 as tracers) visualizes inflamed tissues of AS patients, with clinical scores as reference Secondary aim: To investigate whether reduction of inflammation by…
Office endometrial sampling is not suitable to diagnose EIN due to the small amount of tissue obtained.
We purposefully selected four interventions, three groups with different roles and six countries because we expect acceptability to differ within these dimensions. There are specific hypotheses (H) for part of the possible contrasts. We will explore…
It is expected that coblation treatment has an effect on knee cartilage quality in patients with meniscal lesions and cartilage loosening of the knee
It is our hypothesis that a combined life style intervention of exercise and weight loss will result in a reduction of pain and improvement of function of the affected hip joint, which will postpone a chirurgical intervention.
We expect that patient who receive care according to the protocol about 24/7 availability of specialized palliative care in the home situation, during the year of the study will die more often at home than patients in the years before start of the…
Part 1: effect of depth of anesthesia on motor evoked potentials in spinal surgery Primary Objective: To determine the effect of depth of anesthesia, quantified by pEEG, on the characteristics of TES-MEP measurements in spinal surgery. Hypothesis:…
Donor-specific antibodies form a significant barrier in transplantation of highly pre-sensitized dialysis patients. Increased waiting time is associated with increased morbidity and mortality among these patients. Thus, there is a need to further…
The hypothesis is that low dose GC therapy exerts its anti-inflammatory effect by virtue of a first-pass effect through the liver. It is difficult to directly address the hypothesis, but there is an indirect way of doing so: if indeed low dose GCs…
The EEG profile in responders to methylphenidate will be differ from the EEG profile in non-responders to methylphenidate (i.e. higher total power, increased theta/beta ratio and theta/alpha ratio).
This study aims to establish a plasmakinetic profile of GABA from tomatoes in healthy men and compare it to the kinetic profile of GABA from a supplement. In addition, the effects of glutamate (precursor of GABA) on the plasma-time curves of GABA…
A previous caesarean section does affect the reproductive outcomes including live births in women after In Vitro Fertilization or Intracytoplasmic Sperma Injection.
Primary Objective: The primary aim of the current study is to examine whether CFT is effective for reducing self-criticism in patients with PDs or PTSD. We hypothesize that CFT reduces the level of self-criticism. Secondary Objective(s): To examine…