150 results
We hypothesize that NK and/or T cell-mediated immunotherapy may represent a novel therapeutic option for patients with refractory and/or metastatic ES. Therefore, we will study molecular mechanisms that determine the susceptibility of ES to T and NK…
Primary objectivel: assessment of liver fibrose in children with cystic fibrosis, using transient elastography (Fibroscan). Results will be compared with other surrogate markers of CFRLD: liver ultrasonography and biochemical markers: AST, ALT, PT,…
The effectiveness of Video feedback Intervention to promote Positive Parenting for Autism (VIPP-AUTI) will be investigated on the sensitivity for autism spectrum disorders (ASD) in parents of a child recently diagnosed with ASD, based on the the…
The aim of this study is to describe the values of the SNIP in patients with neuromuscular disease and various respiratory conditions and to assess the practicability of the SNIP in these patients.
This study contributes to the evaluation of the Detection- and Prevention-protocol, as applied by YHC to 5 to 6-year-olds.
The aim of this study is to examine if WB-MRI can replace CT in staging of patients with a malignant lymphoma.
To assess whether the GdMRI can fit in the annual check up.To assess whether the GdMRI is sensitive to monitor and follow up on the peripheral bronchiectasis and areas of hypoperfusion. To compare the distribution and volume of hypo perfusion on…
Determine associations between genetic variation and immune response in nasopharyngeal aspirates of infants with RSV LRTI.
Comparing the reliability of a dietary-protein test with conventional Growth Hormone Stimulation Tests.
To improve the quality of care for children with End Stage Renal Disease by central registration and frequent intervision.
Our preliminary data shows that the prescription rate of antibiotics for suspected EOS versus blood culture proven EOS was high. We aim to develop a new diagnostic model to reduce unnecessary antibiotic treatment which can be tested in the near…
To describe the safety profile of a second dose of ProQuad® manufactured with rHA when administered to children in their second year of life.
To determine the effectiveness of a maintenance treatment by SMS (SMSMT) in overweight and obese children, after a short-term multidisciplinary cognitive behavioural group therapy (CBGT).
To identify risk factors that might contribute to the development of post-traumatic HHD in children in order to reduce the lag-time between onset and diagnosis for future patients. To investigate the level of functioning and the quality of life of…
To assess whether a single shot of dexamethasone reduces postoperative pain, and reduces the time children need to start with drinking and eating.
Primary Objective:To evaluate the efficacy of Oxabact TM to reduce urinary oxalate levels from Baseline to Week 24 in subjects with Primary Hyperoxaluria (PH).Secondary Objectives:To evaluate:* Percentage of subjects who have 20% or greater…
The present research proposal describes a study in 4-year-old boys with the objective to measure the concept of selfcontrol in different ways. It will be studied to what extent these different methods adequately measure selfcontrol, how they are…
To examine the apoptotic response of isolated and cultured airway epithelial cells of infants to a wide variety of cytotoxic agents and potential apoptotic stimulants ex vivo. These include oxygen, nitric oxide, peroxynitrite, cigarette smoke…
To investigate the occurrence of undiagnosed CHARGE syndrome in patients diagnosed with (atypical) Kallmann syndrome and to define criteria for CHD7 analysis in patients with Kallmann syndrome.
The research question targets the validation and examination of norm scores of the ToM test-R test in the mental disorders PDD, ADHD, and social phobia in children of different ages. It will be investigated:(1) Whether or not differences in *theory…