3434 results
Primary Objectives:* To evaluate the effects of therapeutic and supratherapeutic plasma levels of arimoclomol on the heart rate-corrected QT interval (QTc).Secondary Objectives:* To evaluate the effect of arimoclomol on other ECG parameters: heart…
The aim of this pilot study is to investigate whether the developed smartphone app can increase physical activity in PD patients for a short period of time (one month). The secondary aim is to study the usability and enjoyment of the app and the…
The objectives of the study are to describe:1. The efficacy of the Edwards Cardioband Mitral System in improving mitral regurgitation, functional status, and quality of life.2. The safety of the Edwards Cardioband Mitral System.
To determine the effect of salt (NaCl) supplementation on (1) physiological parameters (such as serum potassium) and on (2) clinical signs and symptoms and quality of life.
The primary objective of this study is as follows: -To evaluate the efficacy of 2 remdesivir (RDV) regimens with respect to clinical status assessed by a 7-point ordinal scale on Day 14The secondary objective of this study is as follows: - To…
The objective is to compare the outcome of the ultrathin stent strut Supraflex Cruz stent to the thin stent strut Ultimaster Tansei stent in a PCI population at high risk for bleeding (HBR).
Primary objective: To reduce clinically relevant respiratory tract infections (including COVID-19) ind community dwelling older persons during the pandemic of SARS-CoV-2. Secondary objective: To reduce disease severity, the duration of hospital…
To collect reference data of dEMG in neonates to use for testing the Bambi Belt B.V. algorithm which is under development.
The primary aim of this study is to investigate the added effect of one consecutive week of BRJ consumption on VO2max in prehabilitated patients scheduled to undergo a minimally invasive esophagectomy for cancer.
Primary objective:Does the use of the application support a positive lifestyle development?Secondary objectives:Does the use of the application support an increase in physical activity levels?Does the use of the application has a positive influence…
-To describe the differences in the parameters of physical exertion during physical activity with two different HMEs in both a lab and daily life setting-To asses patients* satisfaction with both types of HMEs
Primary Objective: To determine when straylight stabilizes in eyes after cataract surgery, determine the amount of straylight in eyes implanted with a Clareon monofocal IOL and a Vivinex XY1 monofocal IOL, and compare these straylight values to…
The primary objective is to investigate whether the use of patient-specific cutting guides for an open wedge high tibial osteotomy (HTO) provide a more accurate correction relative to the preoperative planning compared to the conventional osteotomy…
Primary Objective: To study trial feasibility in terms of patient enrollment and the percentage of tumor biopsies that can be assessed successfully.Secondary Objective(s): To study preliminary effects of exercise on immune function and generate…
Primary objectives 1. To evaluate the efficacy, feasibility and safety of G-POEM in patients with symptoms delayed gastric emptying after oesophagectomy with gastric tube reconstruction, based subsequently on the clinical success rate at 3 months,…
To study the effectiveness and safety of administration of FMT on acute pouchitis.
Primary Objective:To evaluate the efficacy of ELX/TEZ/IVA in subjects 6 through 11 years of age with CF, heterozygous for F508del and a MF mutation (F/MF)Secondary Objectives:• To evaluate the PD of ELX/TEZ/IVA• To evaluate the safety of ELX/TEZ/IVA
This study has been transitioned to CTIS with ID 2024-513070-21-00 check the CTIS register for the current data. Primary objectives: Improvement of CR2 rates after induction with ALL R3 with bortezomib versus withoutbortezomib in HR relapsed ALL…
Primary research goal- Evaluate whether resuming activities of hairdressers and catering staff results in a significantly higher percentage that produces antibodies against SARS-CoV-2 after 3 months.Secondary research goals- Identifying determinants…
To study the difference between the vaginal microbiome of fertile women with IBD and healthy controls, as determined by lactobacillus dominance.