176 results
The overall aim of this pilot is to evaluate the technical feasibility and clinical implementation of the Stroke Box by evaluating user experience and hypertension management. The primary objective is gathering data on blood pressure management for…
The primary objective will be to evaluate the sensation of the keloids as measured by Semmes-Weinstein monofilaments (SWM), Pressure Specified Sensory Device (PSSD) and/or Quantitative Sensory Testing (QST), compared between patients with and…
The objective of this study is to:1) explore the feasibility (recruitment, adherence, and absence of major technical problems) of using both medical-grade and consumer grade wearables for continuous measurement of physical activity, posture, balance…
1) To identify T2 low biomarkers and 2) to unravel the mechanisms and downstream effects of Tezepelumab in T2 low asthma.
Part A:- Evaluate the safety of increasing doses of a single dose continuous DMT infusion over 90 minutes in healthy smokers - Characterize the pharmacokinetics of a single dose DMT administered continuously over 90 minutes in healthy smokers -…
The aim of this study is to evaluate the feasibility of the E-TOP module for both VP infants as an addition to the TOP program as well as for MP infants in an adapted TOP program.
Primary objective: to explore the application of automatic STV measurements by the ICD (STV-ARI,automatic), by correlating the STV-ARI,automatic values to the STV-values derived from our clinical gold standard, i.e. STV-QT (STV values derived from…
The aim of this experiment is to investigate whether training reappraisal will prevent stress-induced impairments in effective emotion regulation, and if this training effect is associated with reduced negative effects of acute stress on PFC…
In this study, we will investigate how quickly and to what extent TNO155 is absorbed, transported, and eliminated from the body. TNO155 will be radioactively labeled with carbon-14. In this way, TNO155 can be traced in blood, urine, feces, and…
Primary objectives: - To examine the effects of deep procedural sedation and use of HFNOT on the tcPCO2.- To determine the effects of deep procedural sedation and use of HFNOT on the mitoPO2Secondary Objective: - To determine the effects of deep…
PRIMARY QUESTIONDuring the sentinel node procedure in breast cancer patients, does a 3D SPECT/CT protocol not lead to a longer operation time to remove axillary sentinel nodes, compared to the 2D standard protocol?• H0: OK-time(SPECT/CT) - OK-time(…
Primary Objective: to investigate whether image-based ROSA procedures, which require more preparation time from the surgeon, reduce operation duration and required materials in the operation ward, as compared to imageless procedures, for which ROSA…
The main objective of the current study is to determine the feasibility of spatial and temporal quantification of swirling blood flow inside the SFA of patients treated with the BioMimics 3D stent, using high framerate (HFR) contrast enhanced…
Primary:• To evaluate the efficacy of PTC923 in reducing blood phenylalanine (Phe) levels in subjects with phenylketonuria (PKU) as measured by mean change in blood Phe levels from baseline to Weeks 5 and 6 (ie, the average of each respective…
The primary objective is to compare the IntelLeg Knee on the execution of a subset of daily activities for individuals with a transfemoral amputation to auto-adaptive or mechanical (non-powered) prosthetic knee via musculoskeletal simulation. The…
In this study we will compare different dosing regimens with the study compound JNJ-64281802. We investigate how quickly and to what extent different doses JNJ-64281802 are absorbed, transported, and eliminated from the body when they are given at…
The objective of this study is to validate the tHb determined by sOCT by comparing it to the tHb from invasive blood sampling. From this comparison, we aim to optimize our data analysis procedure for in vivo sOCT measurements. We also aim to…
To determine the difference in amino acid digestibility of milk, sorghum and black beans between older (65-80 years) and younger (20-35 years) adults using the dual tracer method.
The primary objective is to assess the relation between involuntary and voluntary assessed quadriceps muscle endurance in patients with COPD.
To assess the feasibility of a tailored eHealth intervention (primary) for cardiac patients with a low socio-economic position and explore its effect on patient activation, certainty and guidance (secondary) compared to usual care.