176 results
The aim of the study is to investigate the effect of vibrotactile feedback on exoskeleton use in people with complete spinal cord injury.
The objective is to obtain insight into a dose-dependent effect of vitamin K2 on oxidative stress and specific markers of the immune system. The primary objective is to investigate the effect of vitamin K2 on oxidative damage to lipids by measuring…
To assess the safety, tolerability, pharmacodynamics and efficacy of two DLQ02 topical formulations in patients with plaque psoriasis. To assess systemic exposure of CsA and F6H8 after topical application.
In this pilot study, we aim to investigate if increasing field strength beyond 7T will result in additional advantages in characterization of MS lesions in vivo and to identify its limitations and technical challenges. More specifically, firstly, if…
In this study, the Trachospray device will be evaluated with regard to blocking the airway reflexes during awake videolaryngoscopie.
To assess the experienced quality of recovery after day care surgery between patients provided with a smartphone application for remote monitoring and patients receiving standard of care (no remote monitoring).
The goal of this study is to asses wheter testosterone contamination is caused by appliction of testosterone gel on the phlebotomy site or on the forearm.If previously mentioned study is supported by the current study, the testosterone/estradiol…
The aim of this study is to assess the effectivity of the Fluxion, in combination with Bluem (Bluem, Bluem Europe, Zwolle, The Netherlands) and in combination with demineralised water. This aims to find a minimally invasive treatment for peri-…
To determine the effect of SaO2 and PaO2 levels on mitoPO2 and markers of oxygen delivery and consumption in healthy human volunteers.
In this study we will investigate the influence of a high-calorie, high-fat meal on the uptake, breakdown, and elimination of the study compound PHA-022121. We will also investigate how safe PHA-022121 is and how well it is tolerated when it is used…
Primary• To compare the anticholinergic side effects between repeated intravaginal administration of oxybutynin with the vaginal MedRing device and repeated oral administrationSecondary• To explore the pharmacokinetics of oxybutynin and its main…
To investigate whether Astmakompas is feasible, acceptable, easy and safe to use in a secondary care context for both patients and healthcare professionals (HCPs), as well as to investigate its potential effects in improving health and healthcare…
The primary outcome parameters are identification rate of SLN(s) or lymph node metastases with bevacizumab-800CW, defined as the number of patients in which a SLN or lymph node metastasis was detected due to fluorescence during surgery and/or…
Primaire Objective: - To evaluate the safety and tolerability of long-term treatment with the study drug in patients with ALS or FTD with a documented mutation in the C9orf72 geneSecondary Objective: - To evaluate the clinical and pharmacodynamic (…
The primary objective of this study is to investigate the effect of a 6-week colon-delivered multivitamin supplementation on the gut-brain axis in older adults, by assessing changes in brain function (working memory) as well as intestinal changes (…
Primary objective:To demonstrate the non-inferiority (NI) of the humoral immune response in healthy participants 50-59 YOA compared to OA (>=60 YOA) for the RSV-A strain after RSVPreF3 OA investigational vaccine administration.To demonstrate…
Primary:• To evaluate the effect of efgartigimod IV compared to placebo on CRESSSecondary:• To evaluate the effect of efgartigimod IV compared to placebo on the histology of the parotid gland (selected sites only)• To evaluate the safety of…
The primary objective is to evaluate the safety, tolerability, and doselimiting toxicities, and determine the recommended dose for expansionof INCA00186 as monotherapy and of combination treatments of INCA00186 with retifanlimab and/or INCB106385 in…
Main goal:The main goal of the study is to show the feasibility of using Doppler US derived patient specific velocity profile in the abdominal aorta, carotid artery and femoral artery, in order to improve the Fluid-Structure-Interaction models of…
Primary Objective: To assess whether patients with atherosclerosis have more uptake of 68Ga-Dotatate than patients without atherosclerosis. Secondary Objective(s): To correlate 68Ga-Dotatate uptake with the fat attenuation index (FAI), a specific…