166 results on atopic dermatitis
Primary objectives:• To explore whether daily oral treatment with 30 mg prednisolone modulates biomarkers for adverse metabolic effects in a similar manner in patients with chronic atopic dermatitis as compared to healthy volunteers.• To determine…
The research question of the underlying study is: What are the effects of GMA*s on children with atopic dermatitis/ food allergy and their parents as compared with individual visits on:- physical complaints- self management- quality of life
We hypothesize that the long lasting therapeutic effect of coal tar could be mediated by effects on the skin microbiome and/or effects on cellular memory by epigenetic changes. In atopic dermatitis patients, coal tar therapy could modify the skin…
The aim of the project is to gain more insight of the OX40/OX40L expression patterns in atopic dermatitis. This information can be used to adapt the design of subsequent in vitro/ in vivo research, clinical research, but also the development of the…
BIOMAP (Biomarkers in Atopic Dermatitis and Psoriasis) NL is part of the BIOMAP consortium, which is a EU-funded consortium through which various research projects will address three main unmet needs in AD and Pso with a broad impact on disease…
The primary objective of this study is to compare the therapeutical effect on atopic dermatitis of a standard used emollient (Unguentum leniens FNA) compared to a skin barrier repair cream (Dermalex Eczema), assessed by clinical and subjective…
What has so far been underexplored in the study of molecular signatures in atopic dermatitis is a wide systems biology approach, in which multiple analysis techniques (a so-called multi-omics approach) are applied in a clinical setting where…
The primary research question is:Do children with atopic dermatitis and asthma after a stay in the NAD have a better coping and acceptance of their disease as compared with children treated at the outpatient department of the WKZ?Secondary research…
The primary objective is to assess the long-term safety of nemolizumab (CD14152) in adult and adolescent subjects with moderate-to-severe atopic dermatitis (AD).The secondary objective is to assess the long-term efficacy of nemolizumab (CD14152) in…
To objectify skin barrier repair characteristics of coal tar in atopic dermatitis patients, by quantifying changes in NMF, lipid levels, TEWL, SCORAD-score and cytokine levels
Primary Objective: To investigate longitudinal variation of blood-based biomarkers, their integration with disease severity, comorbidities, their association with standard care and characterization of adequate and inadequate responders to standard…
To investigate whether atopic dermatitis patients can be stratified based on integral analysis of clinical patient data complemented by novel biophysical measurements, in-vivo Raman spectroscopy, microbiome swabs and a oral mucosa swab (one time).
To evaluate the additional effect of coal tar treatment to a corticosteroid regimen in adults (aged >16 years of age) with moderate to severe atopic dermatitis, based on the percentage change in Eczema Area and Severity Index (EASI) at week 2…
The use of the oral immunosuppressant Myfortic® in the treatment of atopic dermatitis might be responsible for the delay the repair of DNA-damage in the skin after UV-exposition.
The objective of the study is to assess the long-term safety of tacrolimus ointment 0.03% or 0.1% in the treatment of subjects with atopic dermatitis under actual use conditions, including the risk of developing cutaneous or systemic malignancies.…
Primary study objectiveTo investigate the prevalence of asthma in children up to 7 years of age with atopic dermatitis in infancy who received either Nutrilon Pepti with synbiotics or Nutrilon Pepti without synbiotics during 12 weeks in their first…
We hypothesize that e-health, consisting of internet guided monitoring and self management training online, for patients with atopic dermatitis combines cost savings with an improvement in quality of life.
To determine the frequency and suppressive potential of skin resident regulatory T cells isolated from atopic dermatitis and psoriasis patients compared to healthy control subjects (the latter data will be obtained by co-workers at the Brigham and…
To determine the functional capacities of regulatory T cells present in lesional and non-lesional atopic dermatitis skin, and lesional and non-lesional psoriasis vulgaris skin.
To collect prospective clinical and molecular data on the phenotypical characteristics of patients with atopic dermatitis (AD) receiving standard care targeted systemic treatment.