15 results on atopic dermatitis
To investigate whether atopic dermatitis patients can be stratified based on integral analysis of clinical patient data complemented by novel biophysical measurements, in-vivo Raman spectroscopy, microbiome swabs and a oral mucosa swab (one time).
To explore associations between biomarkers of atopic dermatitis(AD) and:• Disease state and time course of AD,• Disease state and evolution of selected atopiccomorbid conditions,• Effectiveness of specific AD treatments.
To compare the MC with the UK working party diagnostic criteria (UKC) and clinical diagnosis and to refine the MC into a more convenient and reliable set of criteria.
The aim is to validate the hypothesis that a positive history defined as dermatitis at exposure to a scented product and thereafter avoidance of such products in fragrance-hypersensitive individuals and a positive patch test result to fragrances is…
To evaluate the diagnostic performance and safety of metal allergens proposed for inclusion in Metal Panel T.R.U.E. Test. The study will compare the diagnostic performance (primary) and safety (secondary) of ascending patch test doses of aluminum,…
Primary Objectives- To evaluate disease related characteristics in patients with different vulvar conditions compared to healthy volunteers - To evaluate the variability of the selected biomarkers between subjects, and within subjects over time.…
Analyses should indicate whether, in line with our hypotheses, CIM and CPM are improved after effective treatment in patients with chronic itch. When the hypotheses are supported, the study provides preliminary evidence for possible treatment…
The main objective is to evaluate the cytokine response to tape stripping in vivo, dynamically and non-invasively by means of patches..The secondary objectives are (i) to correlate the cytokine response with transepidermal water loss (TEWL), a well-…
The main objective is to evaluate the cytokine response to histamine iontophoresis in vivo, dynamically and non-invasively by means of transdermal analysis patches. The secondary objective is to correlate the cytokine response with morphological…
Primary objective: to identify predicting phenotypical and endotypical biomarkers for the response to dupilumab in adult patients with CRSwNP, by comparing the type 2 inflammation in the peripheral blood and nasal polyp tissue at baseline and after…
Primary Objective: - Investigate whether recirculating tumor-associated tissue macrophages (TiMas), as well as circulating melanoma cells can be detected using high-end flow cytometry methods in peripheral blood from melanoma patients.Secondary…
Primary:To determine the prevalence of pruritis in patients with hidradenitis suppurativa.Secondary:- to evaluate pruritis severity and its effect on three elements of daily activities;- to evaluate differences in extensiveness of HS in relation to…
The primary objectives are to investigate attentional interference by somatosensory itch and pain stimuli in healthy subjects, both on a behavioural (SAT) level and a neurophysiological level (EEG alpha-desynchronization).Secondary objectives…
by improving the understanding of the relationship of CRD to clinical expressions of allergic disease in children, this study aims at generating data that can improve the development of tools that will help the primary or secondary care practitioner…
The primary objective of this study is to determine the prevalence of contact allergies in patients with diabetic foot ulcers.