26 results on atopic dermatitis
Primary Objective To evaluate the safety and tolerability of topical XZ.700 in patients with mild to moderate atopic dermatitis Secondary Objectives To investigate the PD effects of XZ.700 in patients with mild to moderate atopic dermatitis To…
The effectiveness and cost-effectiveness of treatment with systemic cyclosporine or dupilumab in children with moderate-to-severe atopic dermatitis is different for patients with low NMF (corresponding with filaggrine-gene mutation) versus children…
To compare the MC with the UK working party diagnostic criteria (UKC) and clinical diagnosis and to refine the MC into a more convenient and reliable set of criteria.
Wet-wrap treatment with diluted corticosteroids is more effective than wet-wrap treatment with emollients only
Isoleucine is an aminoacid showing in vitro efficacy in increasing keratinocytes to increase the production of Antimicrobial peptides (AMP)such as beta defensine. In AD there is a reduced production of AMP
The primary objective of this study is to compare the efficacy of wet wrap therapy with diluted corticosteroids versus wet wrap therapy with emollients. The secondary objective is to develop an effective and objective value for monitoring the…
It is expected that feeding a new hypoallergenic formula will result in a lower occurrence of AEDS (Atopic Eczema Dermatitis Syndrome) compared to giving a standard formula in infants with a high risk of developing atopic disease. Extension: To…
Aim of this study is to explore the relation between Th1-cell mediated diseases as psoriasis/psoriatic arthritis and Th2-cell mediated asthma, allergic rhinoconjunctivitis, atopic dermatitis and hand eczema. Question is whether a dysbalans in…
The objective of the study is mapping and assessing of the effects of filaggrin mutation on atopic eczema and other atopic diseases together with serological parameters.
Class III corticosteroid is more effective than a class I corticosteroid for treating a moderate flare-up of atopic dermatis in children.
This is a set-up for a challenge pruritus model. We expect to initiate a local, reversible itch- response
In the present study we sought to determine the levels of IL-1 cytokines in the SC and to relate them to FLG genotype, pH and the levels of filaggrin degradation products. Furthermore, we aim to investigate whether FLG genotype status relates to the…
The overall aim of this study is to evaluate objectively measured disease related characteristics in patients with different vulvar conditions compared to healthy volunteers.
The preventive HA formula will show on average a 40% risk-reduction for AD (54% when AD is not present in family history and 22% when AD is present in the family history) as compared to a standard formula. 2) The preventive HA will show a 30% risk…
The primary objective of this study is to assess whether tacrolimus is effective for the treatment of morphea.
prebiotics and fatty acids will decrease the burden of recurrent respiratory infections in children
The primary objective of this study is to evaluate the efficacy and safety of naltrexone in the treatment of itch in patients with burn wounds.
The primary objective of this study is to evaluate the efficacy and safety of naltrexone in the treatment of itch in patients with burn wounds. The nature of the association(s) of the - reduction of the - intensity of itch with sleep and anxiety in…
Primary Objectives • To assess the pharmacodynamic effects of prednisolone on the IMQ-induced inflammatory response • To assess safety & tolerability of topical IMQ in combination with prednisolone Secondary Objectives • To explore…
Primary objectives • To evaluate complement activation after topical imiquimod challenge • To evaluate complement activation after local UV-B challenge