810 resultaten
Intake of chlorogenic acid and trigonelline reduce postprandial glucose concentrations during an oral glucose tolerance test relative to placebo.
The efficacy of reflux inhibitors, which block transient lower esophageal sphincter relaxations (TLESRs), to reduce acid and non-acid exposure may be hampered in the presence of a hiatal hernia, as other mechanisms of reflux become more important.
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…
Doxycycline will ameliorate the vascular condition and inflammatory status in patients with mild to moderate atherosclerotic disease
(1) SNP will reduce the occurrence of psychomimetic side effects during exposure to low]dose ketamine; (2) SNP will reduce the ketamine]induced increase in blood pressure and cardiac output; (3) SNP is without effect on ketamine]induced pain…
S(+)-ketamine influences resting state fMRI in a dose-dependent fashion.
Are there effects of ARA290 and Epo on the ventilatory response to hypoxia. Are there effects of ARA290 and Epo on the gradient over the tricuspid valve during hypoxia a an estimation of the pulmonary artery pressure (PAPA). Does ARA290 and/or Epo…
The primary objective of the present study is to assess efficacy of DBS in the nucleus accumbens for patients with refractory MDD. Secondary objectives are the evaluation of long term efficacy and tolerability of DBS for patients with therapy…
A threshold reduction in LDL-C is required to improve endothelial function as measured by the flow mediated dilation (FMD).
In this randomised, double-blind, placebo-controlled single centre study we propose to study the effect of duodenal infusion of single E. hallii treatment (administered via duodenal tube) on small intestinal gene expression, bacterial composition…
The recently found gene-environment interaction between dietary sodium intake and the ACE genotype with sodium-induced therapy resistance to ACE inhibition in DD homozygotes (that was absent in II and ID subjects) is present in the renal patient as…
Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
We hypothesize that bi-daily 5ml NaCl 7% nebulizations improve respiratory symptoms and quality of life in PCD patients compared to 5ml NaCl 0,9% nebulizations.
1. The effect of a single oral dose of L-000830982 versus oral placebo and an intravenous infusion of ethanol versus placebo on tremor over a 8-hour period in men and women with essential tremor will be estimated; 2. The sensitivity and specificity…
1. The deafferentiation during spinal anesthesia changes the connectivity in resting-state networks in healthy volunteers; 2. The deafferentiation during spinal anesthesia changes pain perception and has sedetive effects.
Chronic chilblains is a common disease causing major restrictions in daily life, nevertheless little is known about treatment. In a literature search, we found thin evidence of three interventions: fluocinolone cream, nifedipine and vitamin D3.…
Lipolysis inhibition during endurance exercise leads to a significantly greater improvement in 24-hour glycemic control in type 2 diabetes, as opposed to endurance exercise under normal circumstances.
Oral exposure time and energy content of the gastric load both affect subjective feelings of satiety and gastric emptying rate. It is expected that a longer oral exposure time and a higher gastric energy content would both increase subjective…
To test the hypothesis that apathy after STN DBS may be reversed by switching the activated contact on the DBS-electrode from a ventral to a more dorsal contact.