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We hypothesize that oral glucose intake and consequently the endogenous induced hyperinsulinemia will lead to insulin-induced microvascular dilatation in healthy normotensive subjects. Furthermore, we suggest that the insulin-mediated microvascular…
What is the effect of carbohydrate infusion on food choice, food intake, satiety, hormones, dependent on the time of day and segment of the small intestine?
The infusion of intrathecal baclofen using higher flow rates results in more extensive intrathecal distribution, hence benefits pharmacodynamic properties of baclofen
5 and 10 grams of a protein hydrolysate effectively increase insulin secretion and lowers plasma glucose levels after a carbohydrate load in type 2 diabetes mellitus (DM-2)
THC causes changes in resting state brain activity that can be visualized by fMRI
In this study we will compare three method to assess the magnitude of the ventilatory response; our hypothesis is that different methods will yield different results.
Investigate whether DWIBS is effective for colorectal cancer screening.
Comparison of the gastrointestinal tolerance of two enteral nutrition formulae
The primary objective of this study is to establish a blood pressure reduction by supplementing hypertensive subjects with an egg white hydrolysate (3g of peptides) and measuring the effects against a placebo.
A possibly competitive inhibition between imatinib and rosuvastatin as substrates for the same solute carriers (i.e. OATP 1A2 and ABCG2) may result in drug-drug interactions and altered pharmacokinetics of imatinib.
Microalbuminuria in diabetes mellitus is not only associated with progression to renal disease, it is also a potent predictor of cardiovascular disease and thus may reflect widespread vascular damage. Endothelial dysfunction is one of the first…
We hypothesized that FFA loading could impair mitochondrial function and that the potency of FFA to disturb mitochondrial function and glucose uptake would depend on the degree of desaturation of the fatty acids infused.
1: Blockade of the angiotensin II AT1-receptor improves the insulin-induced microvascular effects in hypertensive patients. 2: Blockade of the angiotensin II AT1-receptor impairs the insulin-induced microvascular effects in normotensive control…
Paricalcitol induce a more effective reduction of the PTH level compared to alfacalcidol at hemodialysispatients with secondary hyperparathyroidism
Objective: To compare endoscopic pancreatic fluid collection drainage using a standard oblique-viewing US endoscope versus a prototype forward viewing ultrasonic endoscope with emphasis on ease of endoscopic drainage measured by procedural time.
The main hyothesis of the experiments is that a dual action antidepressant (duloxetine) modulates functions in specific brain areas involved in the processing bias of emotional stimuli in the context of neutral versus depressed mood.
The 3 new developed prototype electric brush heads (A,B,C) remove 15% more plaque compared to a EB17 brush head
Doxycycline will ameliorate the vascular condition and inflammatory status in patients with mild to moderate atherosclerotic disease
In the present study we will investigate the efficacy of Lybrido and Lybridos in one group of subjects with FSD using SSRIs in the laboratory and in the domestic setting of these subjects. We will measure subjective, physiological and…
Phytosphingosine decreases cholesterol levels and improves insulin sensitivity