164 resultaten
Different studies have shown that a hunter-gatherer type diet is effective in improving glucose regulation and lipid profile. I want to investigate if the hypothese that this type of diet also reduces the number of physical and psychological…
Inhalation of once daily double dose of inhaled tobramycin targeted to the small airways by the Akita (1x 300 mg instead of 2x 150 mg) is more effective in reducing small airways obstruction compared with standard of treatment: twice daily…
Increasing age is associated with a decrease in step length, gait speed, and mobility. Gait speed predicts numerous clinical conditions, including independence and mortality. A variety of exercise interventions are highly effective in maintaining…
Oral sodium butyrate use in subjects with type 1 diabetes will lead to an altered innate immune system response, ultimately improving beta cell function and glucose regulation.
Use of this walk-bike in daily life extends the range and everyday mobility of IPF patients, thereby decreases the level of dependency and social isolation, factors that are associated with quality of life. If, with this low-cost intervention, daily…
In the process of developing a serious game for testing patients’ level of myocontrol a part of the test needs to be validated. In a previous trial we found differences between several tests that need further inspection. The current study focusses…
1. Methylphenidate (MPH) increases activation in task relevant areas and task performance 2. Hydrocortisone (HC) increases activation in task relevant areas and task performance 3. MPH + HC increase activation in task relevant areas, but might…
The main objective of the FitSupport study is to include 3000 supporters of the soccer clubs into the intervention through two different inclusion strategies; one digital and one personal recruitment strategy. These participants will be divided in…
The alternative hypothesis: there will be a significant difference in HbA1c after receiving a digital health program with information about nutrition and feedback about physical activity behavior, relative to the control group which receives care as…
Modulation of phosphate intake can affect the antiproteinuric efficacy of RAAS-blockade therapy in CKD patients
The aim of this observational study is to investigate a possible difference in systolic and diastolic blood pressure, cardiac output, and prevalence of orthostatic hypotension (OH) after changing positions from supine to standing versus supine to…
Total parathyroidectomy (PTX) in patients with secondary hyperparathyroidism (HPT2) is a more effective treatment than the use of Calcimimetica.
Primary hypotheses The primary hypothesis of the present study is that included patients who receive continuous or intermittent oxygen and bilevel positive pressure ventilation during fixed work rate treadmill exercise tests have shorter recovery…
Bezafibrate will significantly reduce post-prandial non-HDL cholesterol in patients with Familial Dysbetalipoproteinemia compared to placebo.
Our aim is to increase the detection of patients with CRC with familial or hereditary CRC in order to give them an optimal CRC treatment as well as a suitable surveillance advice, and to enable the patient to inform family members about this risk so…
The aim of the current project is to investigate whether positive, strengths- and exception-focused CBT may be a useful supplement or an alternative to the traditional, problem-focused CBT approach for clinically depressed individuals. Primary…
This study aims to chart which thermal challenges modern day humans are exposed to and compare this to their thermoneutral zone. Therefore we hypothesize that modern day humans (both males and females) are predominantly within their thermoneutral…
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…