28 resultaten
A relationship exists between a pharmacologic effect of ENX-201 and the plasma concentration
Administration of a lipid emulsion consisting of long-chain triglycerides (LCT-trial) in non-trained individuals, will induce insulin resistance due to increased DAG accumulation and subsequent activation of the PKC pathway in skeletal muscle.…
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
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We hypothesize that the circulatory and cardiac effects of TEA will be most pronounced during circumstances of increased sympathicotonus, which will be induced by an exercise test on a bicycle.
The formula will be tolerated by at least 90% of the children with cow's milk allergy with a confidence interval of 95%.
Modulation of phosphate intake can affect the antiproteinuric efficacy of RAAS-blockade therapy in CKD patients
Assuming that the use of SDD would result in an estimated infection prevalence of 25%, a difference larger than 10% was to be excluded, hypothesizing an equivalent efficacy of L. plantarum 299/299V plus fibre compared to that of SDD in preventing…
Primary hypotheses The primary hypothesis of the present study is that included patients who receive continuous or intermittent oxygen and bilevel positive pressure ventilation during fixed work rate treadmill exercise tests have shorter recovery…
MRI-ultrasound fusion biopsies of the prostate will detect more clinically relevant tumours (I.e. higher Gleason score) when compared to random ultrasound-guided biopsies in the primary prostate biopsy setting.
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Currently, the effects of nutrition or specific food components, including those on absorption or metabolism, are mostly studied via parameters in blood samples. To reduce the burden for participants of nutritional intervention studies, there is a…
Which of 2 feeding strategies for children during chemotherapy induced mucositis is optimal for the patient: an elementary diet, containing only simple macronutrients administered via continuous enteral drip; or total parenteral nutrition.
The primary objective of this study is to investigate if a specifically designed VR-game is able to activate the pathophysiological substrate associated with OCD in OCD patients, as opposed to healthy controls. This will be investigated by…
We hypothesize that a single night of short sleep duration (4 hours), compared to normal sleep duration (8 hours) reduces metabolic flexibility, increases insulin resistance and thereby reduces HPA-reactivity. Furthermore, we hypothesize that a…
We hypothesize that Iberogast reduces heartburn in patients with functional dyspepsia through an effect on both oesophageal hypersensitivity to acid and on the incidence of reflux episodes.
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…
A nursing nutrition intervention improves protein and energy intake and performance based on hand grip strength compared to usual care.
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…