24 resultaten
Phenotyping of patients with adult onset asthma by linking clinical, functional and molecular markers will: 1. Reveal distinct risk factors of severity and poor quality of life; 2. Provide evidence that recent onset asthma in adulthood is relatively…
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…
Approximately 2% of the Dutch elderly population suffers from a major depressive disorder (MDD). Due to a depressed mood and a diminished interest in nearly all activities, MDD has serious consequences for daily living (e.g. withdrawal from social…
Technology applied to physiotherapy could contribute to identify subgroups in non-specific low back pain patients.
By using a surgical safety checklist, the incidence of postoperative complications will decrease.
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of midazolam.
To determine the sensitivity and specificity and positive and negetive predictive value of MRI in a consecutive series of pediatric patients suspected for acute appendicitis.
1. TGC with insulin in continuous tube fed patients is superior to TGC with insulin in regularly fed patients; 2. Vildagliptin as add-on therapy to insulin mediated TGC results in less hypoglycemic episodes compared to placebo.
Urinary and (peripheral and central) intravenous catheters are widely used in hospitalized patients, although some serious complications can occur with the use of these catheters. Up to 56% of the catheters do not have an appropriate indication. The…
Childhood obesity is an important public health problem. Replacing Sugar Sweetened Beverages by the consumption of water and systematically increasing physical activity levels are promising health behavioral changes that may prevent childhood…
Short-term cognitive behavioral therapy (CBT) given by primary health care workers with patients with chronic benzodiazepine use and new patients in the family practice with sleepinsdisorder, hypothised that CBT results in reduction of…
NAVA (neurally adjusted ventilatory assist) is a newform of artificial respiration, based on the electrical activity of the diafragma. We want to investigate wether there are fysiological differences between the conventional mode and NAVA.
It can be hypothesized that fast track care and/or laparoscopy are associated with less exaggerated inflammatory response during and after surgery resulting in faster recovery of postoperative gastrointestinal motility.
Het is veilig en haalbaar om in 1-2 gastroscopieen zowel een BDstent te plaatsen als brachytherapie toe te dienen.
The new developed brace gives better correction by higher body brace interface pressures than the gold standard Boston brace.
1. What are characteristic (neuro)physiological factors of fatigue in disease-free cancer patients? 2. To which degree can these factors be influenced by Cognitive Behavior Therapy?
We assume that: - Compared to teens in the control condition, those who receive the self-persuasion intervention (motivation condition) will develop more intrinsic motivation, which results in more healthy snacking. - Compared to teens in the…
The aim of the current study is to investigate the effectiveness of two online trainings: action tendency training and selective inhibition training on increasing smoking cessation among Chinese smokes. Hypotheses: 1: It is expected that, for each…
The aim of this study is to develop and evaluate a patient-oriented treatment decision aid (PTDA) focussing on shared goal-setting and decision making, which is tailored to the needs and capacities of a heterogeneous group of patients with type 2…
The aims of the present study are: 1. To give a comprehensive description of 200 adults (> 18 yr) with recently diagnosed adult-onset asthma (< 1 yr); 2. To define clinical, lung function or inflammatory or mixed phenotypes of adult…