138 resultaten
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
About 10-15% of the population suffers from chronic insomnia. Structurally poor sleep can have unpleasant consequences for people's health and quality of life. Therefore, proper treatments are of great importance. Fortunately, Cognitive…
Monitoring a patient’s oxygen status during anesthesia using pulse oximetry is essential. The new Oxygen Reserve Index (ORI) may help provide clinicians real-time visibility to oxygenation in a moderate hypoxic range and serve as a warning of an…
Aim of the study is to determine how often muscle strength measurements should be repeated, using a hand-held dynamometer to obtain a maximal muscle strength measurement
Painreduction for 67% of patients with a locally advanced or local recurrent pancreatic carcinoma through a short radiotherapy scheme (single arm phase 2 study)
There seems to be a biphasic process of bone mineral density (BMD) changes in osetoarthritis (OA). An increased bone mineral density (BMD) and a specific distribution of BMD in the cortical of the subchondral plates and below in the trabecular bone…
Several reasons for clozapine discontinuation are known, but the current evidence identifying patients who are at risk of discontinuation of clozapine is small and not always consistent. Also cultural differences may question if international…
The null-hypothesis predicts that Inlife is not feasible. The alternative hypothesis predicts that the Inlife intervention is evaluated as being feasible. We expect the alternative hypothesis to be true. Inlife will be feasible and minor revisions…
The EuraHS-QoL questionnaire is a valid instrument to measure quality-of-life before and after ventral hernia repair.
Refinement of the CHIP prediction rule will lead to a more efficient use of head CT in patients with minor head injury
The objectives of this pilot are (1) to test and develop an experimental setup to determine contrast sensitivity, visual field and adaptation time at high light conditions. (2) To perform a pilot study with 10 healthy subject.
MIA is a good alternative for the CA, with comparable diagnostic performance. It will lead to an increase in clinical autopsy rates, which have significantly decreased over the last decades in both academic and non-academic medical centers.
To use the GSV for bypass surgery it is of the utmost importance to subtract the vein with as limited damage as possible. To harvest the GSV three techniques are generally used, namely; Standard reversed technique using additional incisions in the…
Objectives are: 1) To determine the feasibility of an OA educational self-management course, by assessing the appreciation of health care providers and participants, participation and barriers and facilitators to participation. 2) To determine…
To analyse the diagnostic and prognostic value of plasma EV protein/miRNA and gene expression profiles of circulating cells for objectified ischemic coronary artery disease in patients with symptoms (e.g. chest pain) suggestive of coronary artery…
Non invasive hemodynamic monitoring is as good as invasive monitoring
To determine the frequency of the most common causes of hospitalizations abroad, repatriation or death of Dutch business and leisure travellers in recent years to identify risk groups for serious health problems.
This project will deliver a user-centred evidence-based patient decision aid, supporting couples with hereditary cancer in their decision making regarding fulfilment of their child wish. The decision aid will facilitate couples with an hereditary…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…