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The objective of this study is to assess the technical feasibility of the EsoFLIP dilation balloon in the treatment of achalasia.
We hypothesize that by stimulation gesture-plus-word combinations the expressive language development will improve.
Laparoscopic Fluorescent near-infrared imaging using ICG can accurately detect liver metastases from uveal melanoma intra operatively.
We expect an improvement in psychological flexibility and a decrease in pain interference in daily life or in fatigue. Furthermore, we expect a decrease in depression and anxiety symptoms.
Think different: effectiveness of an online training for children with obsessive-compulsive disorder
The aim of the present study is to improve treatment for children with OCD by adding an online Cognitive Bias Modification-Interpretation (CBM-I) training as a pre-treatment to cognitive behavioural therapy (CBT). CBM-I is compared with a waitlist…
People with aphasia have problems with communicating. Because communication is very important in the society, these group suffers from a smaller social network, diminished social participation and as a result of this, loneliness, a loss of autonomy…
1. Different neuropathological mechanisms in Parkinson's disease and atypical Parkinsonism concerning the risk of falling; 2. Research concerning the diagnostic accuracy and sensitivity of VEMP and SVV.
Tailored exercise is more effective in regaining functional ability, in comparison to usual care, in adolescents diagnosed with HMS/EDS-HT
We hypothesize that before clinical manifestation of NEC, urine I-FABP, serum GLP1/2, faecal Calprotectin, faecal TLR4 (on shedded enterocytes) and faecal bile acids can be used as predictive markers for NEC. We also hypothesize that Near Infrared…
In this study we explore the feasibility of the sequential use of FLAMSA chemotherapy and T cell depleted reduced intensity conditioning allogeneic stem cell transplantation followed by donor lymphocyte infusion at 3 and 6 months after…
Whole blood thrombin generation measurement is comparable to plasma thrombin generation in clinical setting.
The primary hypothesis is that normo-ovulatory women with a BRCA mutation have lower levels of AMH compared to normo-ovulatory BRCA mutation-negative women, with at least a difference of 0.40 ng/ml, suggesting an effect size of three years in…
Recent pre-clinical experiments demonstrated that sorafenib in Oatp1b2(-/-) mice had 8-fold increased sorafenib-glucuronide blood concentrations.OATP1B1 and 1B3 are highly expressed in the human liver and facilitate the hepatocellular uptake of…
Chronic cold exposure will increase: 1. Basal metabolism and facultative thermogenesis; 2. Brown adipose tissue activity and volume both in obese and diabetic subjects; 3. Skeletal muscle mitochondrial uncoupling and result in BRITE cell recruitment…
A tracer coctail combining indocyanine green and radioactive colloids will allow enhanced detection of the sentinel lymph node in melonoma patients.
Risk stratifying patients in the pre-hospital phase(ambulance or GP) by using the validated HEART score
Anatomical and functional magnetic resonance imaging (MRI) are of additional value to combined 18F-fluorodeoxyglucose positron emission tomography and computed tomography (PET-CT) in the evaluation of treatment response to neoadjuvant chemoradiation…
Protein Supplement, used for extremely-low-birth-weight (ELBW) infants (< 1000 g) in addition to human milk and/or preterm formula in daily practice, is well tolerated and safe.
The primary hypothesis of the study is that there would be no clinical or technical issues preventing MR-HIFU treatments using the Direct Skin Cooling device to be completed successfully.