326 resultaten
The overall objective of this study is to assess safety of AG-348 and provide proof of concept of the efficacy of the drug in SCD patients. Based on currently available data, we hypothesize that the benefits of treatment of sickle cell disease…
In non-COVID-19 patients with pulmonary embolism a prevalence of up to 70% of concomitant symptomatic or asymptomatic deep venous thrombosis has been reported. Physicians experience an exceptionally high prevalence of pulmonary embolism in COVID-19…
Patients with new-onset or recurrent AF have an altered myocardial sympathetic activity. The quantification of sympathetic activity with 123I-mIBG scintigraphy, as well as its change over time after restoration of sinus rhythm, can be used to target…
Observational study
Similar or better fixation, migration and functional outcomes compared to other existing techniques
We hypothesise that the health behaviour of pregnant women is influenced by the measures to prevent the spread of COVID-19. It is not clear however, if it is positively affected (because of having more time, providing online options, creating a…
To determine the feasibility of the measurement protocol of a large prospective longitudinal study to describe the exercise capacity and physical functioning of critical illness survivors up to 5 years after discharge from the ICU.
We expect relatives to be satisfied about the last period of life after non-operative management of the hip fracture.
Colloid Oncotic Pressure as indicator of hemodilution in cardiac surgery with cardiopulmonary bypass
The addition of albumin or gelofusine in the predominantly crystalloid prime is beneficial for COP compared to the crystalloid only prime in cardiac surgery setting with cardiopulmonary bypass.
It is hypothesised that both laser devices will be highly comparable
Implant survival rate of 90% or higher
A minimally invasive endoscopic step-up approach remains preferable over the surgical step-up approach to treat infected (peri)pancreatic necrosis. In the long term we expect no differences in the primary endpoint composite of death and major…
We think that not every patient with a paracetamol intoxication might need the high dose of acetylcysteïne antidote we are used to dose in the Netherlands
It is hypothosized that interventions, which will be developed and implemented in co-creation, improve PA in patients on Surgery, Internal Medicine and Cardiology hospital wards.
It is feasibility to collect activity data, vital signs, and PROMS using a comprehensive online monitoring platform that consists of a wearable activity monitor, digital thermometer, and smartphone-app in patients with advanced melanoma undergoing…
ERCP discharge algorithm combined with UT-2 dipstick test (with a cutoff value of 50µg/ml) can accurately distinguish between groups warranting early discharge and those warranting observation post-ERCP.
1) The incidence of neurological symptoms is higher in COVID-19 patients than in non-COVID-19 patients. 2) The incidence of progression to respiratory failure is higher in COVID-19 patients with neurological symptoms as compared to COVID-19 patients…
Asthma patients experience more anxiety during COVID-19 compared to a stable timepoint in the past.
None, observational study
RR with prompting results in a higher rate of self-initiated toileting and a decrease in urinary/faecal accidents. The addition of overlearning will result in better maintenance of the acquired skills over time.