27 resultaten
Background: Injury rate and injury severity of elderly cyclists due to self-induced cycle accidents increase with age. Starting at the age of 55 years, injury risk increases with a factor 4 at the age of 75 years. Injury mechanisms such as slippery…
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
The hypothesis is that rhGH treatment in children with KS results within 6 weeks in a change of metabolism recognizable as an increase of total energy expenditure (TEE). This change in metabolism can be used as a predictor of growth response in the…
Antipsychotics (haloperidol) can cause acute changes in cardiovascular functions, metobolic parameters and platelet aggregation in elderly patients.
In patients with side effects, during VNS, there is: 1. A decrease in lung function parameters; 2. A reduced increase in heart rate; 3. A reduced increase in blood pressure.
Recurrent miscarriages is defined as three or more consecutive miscarriages prior to the 20th week of gestation. Whenever the diagnosis ‘recurrent miscarriages’ is established, an underlying cause may be identified in about 25-50% of cases. A…
Despite good results of primary total knee arthroplasty (TKA) the number of revision total knee arthroplasties (rTKAs) is rising and a further increase is predicted. rTKA is a more complicated surgical procedure compared to primary TKA and leads to…
The hypothesis of this study is that segmental kyphosis can be maintained after removal of the short-segment pedicle-screw instrumentation in biological young patients with traumatic thoracolumbar burst fractures. In these patients in addition to…
We expect that irrational thoughts and maladaptive coping strategies will be positively changed. As a consequence of this intervention, there should be a significant decrease of: 1. The amount of cyber bullying victims; 2. The psychosocial problems…
The hypothesis is that all patients with rising RT-qPCR MRD levels of specific genetic markers in pediatric AML patients in CR1 invariably will develop overt clinical relapse.
3D information from CT and MRI can be used as gold standard on the quantity to be computed from a mammographic projection image.
We hypothesise that Origo, an experience design concept that supports the woman during labor in a personal and unobtrusive way by providing real-time breathing support and visualizing progress of labor, will enhance the woman s labor &…
1. To estimate the percentage of quantitative RT-PCR negative pediatric CML patients in which Imatinib discontinuation result in sustained complete molecular remission; 2. To determine whether restarting of Imatinib or another tyrosine kinase…
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Nilotinib plus PegIFN will increase depth of response in CML patients who have stable responses above 0.01%.
Electrical stimulation of the sympathetic pathways by cervical spinal cord stimulation increases cerebral blood flow.
1. A meal consisting of harder-textured foods leads to lower energy intake at a lunchtime meal compared to a meal with softer-textured foods; 2. The decreased energy intake of the meal composed of harder-textured foods will not be compensated at the…
[11C]Erlotinib pharmacokinetics may be comparable between non-small cell lung cancer patients with and without erlotinib therapy.
We hypothesize that treatment with collagenase clostridium histolyticum (CCH) injections will also be effective and show significant improvement in outcomes for patients with DD with contractures of the thumb and first webspace.