225 resultaten
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
1. The point of the skin with best possible transcutaneous nerve stimulation correlates with the point of the skin most superficial to the nerves stimulated within a range of 3 mm; 2. Ultrasound will reveal a significant number of sensitive…
A two month distraction period results in similar clinical beneficial effects as a three month distraction period.
1. To develop (cost-) effective implementation strategies which are feasible in daily practice; 2. To test the guidelines in a multicentre effectiveness trial; 3. To develop general quality indicators with appropriate measuring tools for diagnostic…
Is there a difference in the recurrence rate if you treat a cyst or abscess of the bartholin gland with a marsupialization or placement of a word catheter.
We hypothesize that subjects suffering from hypothalamic dysfunction may have a hyposerotonergic neurotransmission. Therefore we will investigate if there are differences in specific hypothalamic-to-nonspecific [123I]FP-CIT binding ratios using…
N/A
If the 'level of fitness dependant protocol' produces a higher VO2-max in comparison with the adapted Bruce protocol, then a relevant difference can be shown when the results are statistically analysed.
The objective of the study is to identify factors associated with anterior knee pain after primary total knee replacement.
A positive effect of the study product in preventing asthma like symptoms in infants at high risk for developing asthma later in childhood.
Is diagnostic non-invasive coronary angiography with MS-CT a cost-effective alternative to diagnostic invasive coronary angiography in the management of patients with stable and unstable angina pectoris, referred for evaluation of the presence of…
What is the contribution of the serum markers sFlT-1 and PlGF in the diagnosis and management of pre-eclampsia.
What is the prevalence of dysplasia or carcinoma in patients with Crohn's disease that undergo surveillance endoscopy with chromoendoscopy-guided confocal laser endomicroscopy?
To study the accuracy of the PISAPED perfusion scan criteria compared with CT scanning in patients aged < or = 50 years with suspected pulmonary embolism, a likley or high clinical probability and/or an abnormal D-dimer.
We propose that kinase activity profiling may be a potential clinical diagnostic tool to predict for tumor response to targeted therapy with tyrosine kinase inhibitors (TKI's).
The pharmacotherapeutic treatment of patients with cancer is generally associated with multiple side-effects. The cause of the side-effects is usually due to the toxicity of the drugs themselves. In addition, drug interactions can intensify side-…
Tumor response from erlotinib and bevacizumab as first line treatment in advanced NSCLC will result in “non-progressive disease” within 6 weeks in more than 50% of patients.
MR Elastography can be used as a non-invasive tool to diagnose, stage and monitor liver fibrosis. MR Elastography has a better accuracy than FibroScan for the assessment of intermediate fibrosis stages.
There might be biomarkers in infected synovial tissue which have predicting value on the effectiveness of Abatacept on RA.