246 resultaten
Background: Injury rate and injury severity of elderly cyclists due to self-induced cycle accidents increase with age. Starting at the age of 55 years, injury risk increases with a factor 4 at the age of 75 years. Injury mechanisms such as slippery…
Fluorescent near-infrared imaging can be used to identify the ureters using a low dose methylene blue.
It is hypothesized that participants who received information about social modeling effects in the intervention group consume less (snack) food compared to participants in the control group.
A two month distraction period results in similar clinical beneficial effects as a three month distraction period.
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
1. That adherence to the WHO recommendations (2003) for early child feeding among low-income Quetzaltenango mothers, specifically exclusive breastfeeding up to 6 months, is associated with higher growth attainment and greater disease resistance; 2.…
Chronic cold exposure will increase: 1. Basal metabolism and facultative thermogenesis; 2. Brown adipose tissue activity and volume; 3. Skeletal muscle mitochondrial uncoupling and result in BRITE cell recruitment.
Intra-operative evaluation of efficacy and safety of a new lead for steering Deep Brain Stimulation.
Primary Hypothesis: 1. Sapiens lead is able to provide stimulation to the brain safely and elicit equivalent effects as commercial DBS systems. Secondary Hypotheses: 1. Steering can modulate the thresholds of stimulation-induced effects; 2. The…
1. To develop (cost-) effective implementation strategies which are feasible in daily practice; 2. To test the guidelines in a multicentre effectiveness trial; 3. To develop general quality indicators with appropriate measuring tools for diagnostic…
For patients with a diffuse large B cell lymphoma (DLBCL) the efficacy of the anti-CD20 monoclonal antibody rituximab combined with salvage chemotherapy in the second-line setting has decreased due to more effective first-line treatment with…
If the 'level of fitness dependant protocol' produces a higher VO2-max in comparison with the adapted Bruce protocol, then a relevant difference can be shown when the results are statistically analysed.
The objective of this thesis is to get insight into the effects of internal audits on patient safety and on health care professional’s behavior in an academic hospital at ward level.
Is diagnostic non-invasive coronary angiography with MS-CT a cost-effective alternative to diagnostic invasive coronary angiography in the management of patients with stable and unstable angina pectoris, referred for evaluation of the presence of…
N/A
The hypothesis is that rhGH treatment in children with KS results within 6 weeks in a change of metabolism recognizable as an increase of total energy expenditure (TEE). This change in metabolism can be used as a predictor of growth response in the…
The number of people undergoing total hip or total knee surgery is growing. The majority of these patients has a favorable outcome with respect to pain, function and quality of life. In a small group of patients however the results are disappointing…
Tumor response from erlotinib and bevacizumab as first line treatment in advanced NSCLC will result in “non-progressive disease” within 6 weeks in more than 50% of patients.
The annual incidence of castration-resistant prostate cander (CRPC) in the Netherlands is estimated at 2868 patients. After development of CRPC, survival with best supportive care is not expected to exceed 12 months. Fortunately, several new…
Influenza-like-illness (ILI) is not only caused by an influenza virus infection, but also by other pathogens, both viral and bacterial. In this study nose and throat swab samples will be taken during ILI episodes to identify pathogens causing ILI in…