240 resultaten
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
1. The point of the skin with best possible transcutaneous nerve stimulation correlates with the point of the skin most superficial to the nerves stimulated within a range of 3 mm; 2. Ultrasound will reveal a significant number of sensitive…
Mechanical bowel preparation (MBP) is common practice in elective colorectal surgery. In recent literature the value of MBP is subject of discussion. This non-inferiority, randomized study evaluates the value of MBP before colorectal surgery.
A specific set of variables of impairments are related/ predictive of functional limitations and disabilities. A specific set of variables of functional limitations are related/ predictive of disabilities. Psychological variables (defined by TPB,…
To evaluate the response to adalimumab treatment in TNF-alpha blockade naïve patients and patients who failed prior other anti-TNF-alpha treatment and to understand the mechanisms underlying the clinical response to TNF-alpha blockade.
Heart rate variability measures correlate with pain intensity in patients with advanced cancer.
Is there a difference in the recurrence rate if you treat a cyst or abscess of the bartholin gland with a marsupialization or placement of a word catheter.
We hypothesize that subjects suffering from hypothalamic dysfunction may have a hyposerotonergic neurotransmission. Therefore we will investigate if there are differences in specific hypothalamic-to-nonspecific [123I]FP-CIT binding ratios using…
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Botulinum toxin type A injection of the prostate causes relaxation and cellular apoptosis and by this way will relieve lower urinary tract symptoms in patients with benign prostatic hyperplasia.
The objective of the study is to identify factors associated with anterior knee pain after primary total knee replacement.
A positive effect of the study product in preventing asthma like symptoms in infants at high risk for developing asthma later in childhood.
What is the contribution of the serum markers sFlT-1 and PlGF in the diagnosis and management of pre-eclampsia.
What is the prevalence of dysplasia or carcinoma in patients with Crohn's disease that undergo surveillance endoscopy with chromoendoscopy-guided confocal laser endomicroscopy?
To study the accuracy of the PISAPED perfusion scan criteria compared with CT scanning in patients aged < or = 50 years with suspected pulmonary embolism, a likley or high clinical probability and/or an abnormal D-dimer.
1. In the first intervention group, the % of subjects who meet the national physical activity guideline will significantly increase; 2. In the second intervention group the % of subjects who meet the national physical activity guideline will…
We propose that kinase activity profiling may be a potential clinical diagnostic tool to predict for tumor response to targeted therapy with tyrosine kinase inhibitors (TKI's).
The pharmacotherapeutic treatment of patients with cancer is generally associated with multiple side-effects. The cause of the side-effects is usually due to the toxicity of the drugs themselves. In addition, drug interactions can intensify side-…
We hypothesized that forming implementation intentions may increase levels of physical activity.
MR Elastography can be used as a non-invasive tool to diagnose, stage and monitor liver fibrosis. MR Elastography has a better accuracy than FibroScan for the assessment of intermediate fibrosis stages.