17 resultaten
A specific set of variables of impairments are related/ predictive of functional limitations and disabilities. A specific set of variables of functional limitations are related/ predictive of disabilities. Psychological variables (defined by TPB,…
Heart rate variability measures correlate with pain intensity in patients with advanced cancer.
1. The intervention group will have a lower BMI/waist circumference, compared to the control group at follow-up; 2. The intervention group will have more favourable outcomes on the targeted behaviours, compared to the control group at follow-up; 3.…
1a. Changes in outcome measures of anxiety can be partly explained by changes in self-reported thougths; 1b. Changes in outcome measures of anxiety can be partly explained by changes in selective attention and by changes in fear relevant cognitive…
The optimal management of locoregionally advanced NSCLC is evolving. Multimodality treatment is rapidly becoming the most common approach to stage III NSCLC. ASCO guidelines recommend initial chemotherapy (platinum-based, 2 or 3 cycles) combined…
Non-inferiority hypothesis: observation is not inferior to operation with respect to the mean of pain and discomfort during 3 years follow-up.
Children born small for gestational age (SGA) might be at increased risk for developing hypertension, cardiovascular disease and diabetes mellitus type 2. It has been shown that those SGA children with relatively higher GH levels during an overnight…
HIV infected patients receiving HAART have an increased risk for cardiac events/disease. In HAART naive patients increased arterial stiffness is substrate for this higher risk. In this study we investigate whether increased risk for cardiac events…
Based on studies in other types of cancer in humans where beneficial effects were obtained, and based on our pre-clinical data in a mouse model for malignant mesothelioma (MM), it now seems feasible and warranted to introduce dendritic cell (DC)-…
The prevalence of Growth Hormone Deficiency in Autoimmune Thyroid Disease is higher than in the general population
p53 mutation in colorectal cancer provides an immunological window for immune therapy.
After allogeneic stem cell transplantation (SCT) the hematopoiesis is from donor origin. Laboratory and animal studies suggests that de dendritic cells of host origin are important in inducing graft versus myeloma effect and graft versus host…
The large implementation of SMOCC will be more (cost-) effective than the usually applicated basic dissemination strategies for guidelines.
1. The number of circulating endothelial (progenitor) cells may be reduced during chemotherapy and correlate to the development of cardiovascular disease; 2. Oxidative stress due to chemotherapy may lead to an increased accumulation of Advanced…
Plasmalogens can be synthesized out of batyl alcohol (naturally occuring alkylglycerol) in patients with the peroxisomal disorder rhizomelic chondrodypslasia punctata (RCDP), bypassing the peroxisomal steps in the pathway.
The principal aim of this research project is to establish the origin of increased echogenicity in the thalami and basal ganglia (ED/TDG), an ultrasonographic finding fequently encountered in very preterm infants. It is not known whether ED/TBG is a…