100 resultaten
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
H1: the exercise intervention is effective in reducing (work-related) fatigue H2: the exercise intervention is effective in improving (work-related) self-efficacy, sleep quality, work ability, cognitive functioning, and aerobic fitness.
Informed consent procedures and information provision differs between different transplantation centers and transplantation professionals in The Netherlands. Donor knowledge and satisfaction may be influenced by the manner of information provision…
There seems to be a biphasic process of bone mineral density (BMD) changes in osetoarthritis (OA). An increased bone mineral density (BMD) and a specific distribution of BMD in the cortical of the subchondral plates and below in the trabecular bone…
To analyse the diagnostic and prognostic value of plasma EV protein/miRNA and gene expression profiles of circulating cells for objectified ischemic coronary artery disease in patients with symptoms (e.g. chest pain) suggestive of coronary artery…
We hypothesize that the active strategy leads to a better functional outcome than the conservative strategy three months after acute ischemic stroke, in patients with elevated pre-treatmen blood pressure otherwise eligible for intravenous…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
•To assess the safety and tolerability of induction doses of ABP-700 and determine dosing regimens that reliably produce drug induced unconsciousness and the pharmacodynamic conditions necessary for induction of general anesthesia with ABP-700 alone…
The rationale for this study is to assess the visibility and positional accuracy of the laser marks. Combined with VLE imagery, the targeting enabled by the laser marking system could have the potential to increase the diagnostic accuracy of current…
We hypothesize that SNNS might be of great value in early esophageal cancer, especially in the treatment of high-risk early EAC (T1b-tumors). A treatment algorithm consisting of endoscopic resection of the tumor, followed by SNNS and (adjusted) LN…
Differences in the healthcare, workplace, legislative, and personal systems (see figure) as well as evaluator and patient characteristics may better explain differences in FCE results
We hypothesise that accurate treatment of GOLD D patients in an integrated primary care system will improve patient outcomes over 12 months.
In the process of developing a serious game for testing patients’ level of myocontrol a part of the test needs to be validated. This validation is the goal of the current study. The part of the test that needs to be validated focusses on the…
PolyEthylene Glycol with ascorbic acid (PEG-asc) bowel cleansing preparation could contribute to the development of low potassium values. Hypokalemia is partially a pre-existing matter before bowel cleansing. Elderly are at risk for development of…
We expect to find differences in taste related brain regions, i.e. the primary and secondary taste cortex (AIFO and OFC) and brain regions involved in reward and energy processing, such as the striatum, amygdala and cingulate cortex.
Radium-223 is the 5th treatment for metastasized castration resistant prostate cancer with a proven overall survival benefit. The improved survival of Radium-223 over placebo was demonstrated in the ALSYMPCA trial, which included a miscellaneous…
Visceral obesity and sarcopenia are associated with increased risk of postoperative complications in colorectal cancer surgery.
High B-value diffusion weighted MR imaging at 1.5T has sufficient quality to be considered as addition to lower b-values in order to increase diagnostical value of the dussion weighted imaging series.
Preoperative use of a prediction model in breast cancer patients, concerning tumour volume versus breast volume ratio and tumour localisation, improves cosmetic results in breast conserving surgery