4945 resultaten
The primary objective of this study is to determine whether treatment with statins reduce the progression of aortic stenosis in young adult patients with congenital aortic stenosis.
Colesevelam is a bile sequestrant that not only improves lipid parameters, but also improves glycemic control. The workingsmechanismen of colesevelam is yet unknown. We hypothezize that treatment of obese insulin resistant subjects with colesevelam…
1. Addition of weekly pegvisomant administrations improves quality of life; 2. Addition of weekly pegvisomant administrations improves insulin sensitivity.
Healthy volunteers and patients with a high variability in pain scores have a high probability to experience pain relief from alfentanil opposed to volunteers and patients with a low variability in pain scores.
The main hyothesis of the experiments is that a dual action antidepressant (duloxetine) modulates functions in specific brain areas involved in the processing bias of emotional stimuli in the context of neutral versus depressed mood.
This study hypothesizes that doxapram will protect preterm infants from both invasive ventilation (and related lung disease) and apnea of prematurity related hypoxia (and related impaired brain development).
SCH 351125 50 mg BID 2/days is an effective treatment for RA.
Xylometazoline nasal spray realizes vasoconstricion in the nasal mucosa, which will be assessed and visualized using SDF imaging.
A protein supplement has a positive effect on muscle mass, muscle strength and physical functioning during a weight loss trial in overweight elderly.
The present study is a feasibility study. In this study we will test the feasibility of the procedures used, the compliance to the interventions, and the usefulness of intermediate outcome measures in a specific high risk group. If the results of…
Recent research shows that obesity is associated with changed bowel flora composition with a relative abundance of the two dominant bacterial divisions, the Bacteroidetes and the Firmicutes. Interestingly, this specific bacteria associated condition…
Although vitamin D is well known for its function in calcium homeostasis and bone mineralisation, several studies have shown an effect on pulmonary function and incidence of airway infections. Vitamin D deficiency is a common problem in patients…
Repeated feedback reports in which the volume and quality of referrals is discussed will lead to fewer non-rational referrals.
Mood monitoring using smartphones has no clinically relevant effect on low mood.
Type 2 diabetes is a major threat to human health. Disruption of the circadian timing system is associated with metabolic changes. Disturbance of the daily light and dark rhythm could contribute to this phenomenon and effects metabolic pathways. We…
Maraviroc, by a yet unknown mechanism, stimulates immune recovery by increasing CD4+ cell count.
31-3-2014 Hypothesis: Early administration of 5 mg of Metoprolol is associated with a relative 20% reduction in infarct size as measured by cardiac Troponin-T, a total of 408 patients will be enrolled and randomized. Interventions: 5 mg intravenous…
We hypothesize that ketamine stimulates breathing and reverses opioid-induced respiratory depression.
We hypothesize that the opioid analgesic fentanyl will cause hyperalgesic responses when administered during naloxone infusion.